RBRC10950, C57BL/6-Tg(CAG-Sphk1)H1Ytkw

RBRC No. RBRC10950
Type TransgeneCartagena
Species Mus musculus
Strain name C57BL/6-Tg(CAG-Sphk1)H1Ytkw
Former Common name Sphk1 transgenic mice (Tg line: High)
H-2 Haplotype No Data
Background strain No Data
Appearance
1 Appearance No Data
Genotype No Data
Strain description No Data
Health Report No Data
Gene Details
Promoter CAG promoter (CMV-IE enhancer, chicken beta-actin promoter, rabbit beta-globin genomic DNA)
1 Symbol Sphk1
Symbol name sphingosine kinase 1
Chromosome UN
Common name No Data
Symbol description No Data
References No Data

Research applications No Data
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
Prior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form.
In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested.
Cardiovasc Res. 2010 Feb 1;85(3):484-93. doi: 10.1093/cvr/cvp312
Additional information
1 No Data
Depositor Takuwa, Yoh (Kanazawa University Graduate School of Medical Science) Takuwa, Yoh
Strain Status /
Availability
(Expected delivery)


Preparing for distribution
Preparing for distribution
(Please note that it may take more than 6 months to make arrangements to distribute.)

Frozen
Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months

RBRC10963, B6.129-Tg(Nanog-RFP)2Szki

RBRC No. RBRC10963
Type TransgeneCartagena
Species Mus musculus
Strain name B6.129-Tg(Nanog-RFP)2Szki
Former Common name Nanog-RFP Tg mouse
H-2 Haplotype No Data
Background strain No Data
Appearance
1 Appearance No Data
Genotype No Data
Strain description No Data
Health Report No Data
Gene Details
Promoter No Data
1 Symbol No Data
Symbol name SV40 polyA
Chromosome UN
Common name No Data
Symbol description No Data
Promoter mouse Nanog promoter
2 Symbol RFP
Symbol name Discosoma sp. Red Fluorescent Protein
Chromosome UN
Common name No Data
Symbol description No Data
References No Data

Research applications Fluorescent Proteins/lacZ System
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
Prior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form.
In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested.
Genesis, 57, e23334 (2019).
In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested.
The availability of the BIOLOGICAL RESOURCE is limited to a RECIPIENT of a not-for-profit institution for a not-for-profit research. The RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE.
Additional information
1 No Data
Depositor Suzuki, Atsushi (Medical institute of bioregulation, Kyushu University) Suzuki, Atsushi
Strain Status /
Availability
(Expected delivery)


Preparing for distribution
Preparing for distribution
(Please note that it may take more than 6 months to make arrangements to distribute.)

Live
Live mouse :

RBRC06537, B6.Cg-Cdkal1<tm1.1Hko>

RBRC No. RBRC06537
Type Targeted MutationCartagena
Species Mus musculus
Strain name B6.Cg-Cdkal1<tm1.1Hko>
Former Common name Cdkal1 ΔloxP, B6-Cdkal1 KO
H-2 Haplotype No Data
ES cell line M1 [(C57BL/6 x 129)F1]
Background strain No Data
Appearance
1 Appearance No Data
Genotype No Data
Strain development Developed by Haruhiko Koseki, RIKEN Center for Integrative Medical Sciences. M1 ES cell were used to generate the mutant mice. Exon 4 and neo cassette were removed by crossing with CAG-Cre mice (C57BL/6 background).
Strain description Cdkal1 gene knockout mice. Exon 4 was removed. Details unknown.
Colony maintenance Heterozygote x Wild-type [C57BL/6JJcl]
Health Report No Data
Gene Details
Promoter No Data
1 Symbol Cdkal1
Symbol name CDK5 regulatory subunit associated protein 1-like 1
Chromosome 13
Common name No Data
Symbol description No Data
2 Symbol loxP
Symbol name phage P1 loxP
Chromosome 13
Common name No Data
Symbol description No Data
References Unpublished

Research applications Cre/loxP system
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE.
Additional information
1 No Data
Depositor Koseki, Haruhiko (RIKEN Center for Integrative Medical Sciences (IMS)) Koseki, Haruhiko
Strain Status /
Availability
(Expected delivery)


Sperm
Cryopreserved sperm : Within 1 month
Recovered litters from cryopreserved sperm : 2-4 months

RBRC06556, B6(D2)-Sufu<Rgsc2062>

RBRC No. RBRC06556
Type Chemically-induced Mutation
Species Mus musculus
Strain name B6(D2)-Sufu<Rgsc2062>
Former Common name SufuT396I, B6-Sufu/T396I
H-2 Haplotype No Data
Background strain C57BL/6JJcl
Appearance
1 Appearance No Data
Genotype No Data
Strain development Developed by Shigeru Makino and Yoichi Gondo, RIKEN BioResource center. Generated by RIKEN ENU-based gene driven mutagenesis. The mutant mice were backcrossed to C57BL/6J.
Strain description Sufu gene ENU mutant mice. Sufu<Rgsc2062>(T396I variant)(RBRC06556): Homozygous mutant mice are embryonic lethal. Sufu<Rgsc2075>(R396X variant)(RBRC06557): Homozygous mutant mice die around E10.
Colony maintenance Heterozygote x Wild-type [C57BL/6JJcl]
Health Report No Data
Gene Details
Promoter No Data
1 Symbol Sufu
Symbol name suppressor of fused homolog (Drosophila)
Chromosome 19
Common name No Data
Symbol description No Data
References Nat Rev Genet. 2008 Oct;9(10):803-10.

Trends in large-scale mouse mutagenesis: from genetics to functional genomics.
Research applications Cancer Research,
Developmental Biology Research,
Neurobiology Research
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested.
後日指定。(will be announced).
Additional information
1 No Data
Depositor Gondo, Yoichi (RIKEN, BioResource Center) Gondo, Yoichi
Strain Status /
Availability
(Expected delivery)


Sperm
Cryopreserved sperm : Within 1 month
Recovered litters from cryopreserved sperm : 2-4 months

RBRC06572, B6.Cg-Tg(Crx-EGFP)G3Tfur

RBRC No. RBRC06572
Type TransgeneCartagena
Species Mus musculus
Strain name B6.Cg-Tg(Crx-EGFP)G3Tfur
Former Common name No Data
H-2 Haplotype No Data
Background strain No Data
Appearance
1 Appearance No Data
Genotype No Data
Strain development Developed by Takahisa Furukawa, Osaka Bioscience Institute in 2008. The BAC-Crx-EGFP transgene was injected into the pronuclei of B6C3F1 fertilized eggs.
Strain description BAC-Crx-EGFP transgenic mice. This transgenic mouse expresses EGFP in the retina under the control of the mouse Crx promoter. 129 background (RBRC05560), C57BL/6 mixed background (RBRC06572).
Colony maintenance Carrier x Noncarrier [or Crossing to C57BL/6JJcl]
Health Report No Data
Gene Details
Promoter No Data
1 Symbol EGFP
Symbol name Enhanced Green Fluorescent Protein, F64L and S65T (Jellyfish)
Chromosome UN
Common name No Data
Symbol description No Data
References

Research applications Fluorescent Proteins/lacZ System
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested.
Biochem. Biophys. Res. Commun., 392, 317-322 (2010).
Prior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must contract an MTA with the DEPOSITOR (Osaka University).
Additional information
1 GFP Transfer License (Japanese / English)
Please fill in the Schedule A, and submit two signed copies to us together with two signed copies of RIKEN BRC’s MTA. Please also read Schedule B.
Depositor Furukawa, Takahisa (Osaka Bioscience Institute) Furukawa, Takahisa
Strain Status /
Availability
(Expected delivery)


Sperm
Cryopreserved sperm : Within 1 month
Recovered litters from cryopreserved sperm : 2-4 months

RBRC06589, C57BL/6-Tg(Gt(ROSA)26Sor-C1V1/EYFP)1.1Imayo

RBRC No. RBRC06589
Type TransgeneCartagena
Species Mus musculus
Strain name C57BL/6-Tg(Gt(ROSA)26Sor-C1V1/EYFP)1.1Imayo
Former Common name R26 BAC::pCAG-LoxP-C1V1-EYFP, B6-ROSA26/C1V1-YFP/loxP Tg
H-2 Haplotype No Data
Background strain No Data
Appearance
1 Appearance No Data
Genotype No Data
Strain development Developed by Itaru Imayoshi, Institute for Virus Research, Kyoto University in 2012. The transgene was injected into the pronuclei of C57BL/6 fertilized eggs.
Strain description C1V1-EYFP(E122T/E162T) is expressed after both Cre- and FLP-recombination. The transgene construct is knocked into Rosa26 BAC. This modified BAC was used for Tg mouse production. To achieve high-level transgene expression, C1V1-EYFP is expressed under CAG promoter and WPRE sequence is inserted into 3'UTR region. R26 BAC::pCAG-LF-C1V1-EYFP line (RBRC06588), R26 BAC::pCAG-LoxP-C1V1-EYFP line (RBRC06589) (FRT-Stop-FRT cassette was removed by crossing pCAG-FLPe strain), R26 BAC::pCAG-FRT-C1V1-EYFP line (RBRC06590) (LoxP-Stop-LoxP cassette was removed by crossing TNAP-Cre strain).
Colony maintenance Carrier x Noncarrier [C57BL/6JJmsSlc]
Health Report
Gene Details
Promoter No Data
1 Symbol No Data
Symbol name beta-globin poly A signal (Rabbit), SV40 late polyA signal, HSV thymidine kinase polyA signal, SV40 early polyA signal
Chromosome UN
Common name No Data
Symbol description No Data
2 Symbol EYFP
Symbol name Enhanced Yellow Fluorescent Protein (Jellyfish)
Chromosome UN
Common name No Data
Symbol description No Data
3 Symbol Frt
Symbol name yeast FRT (flippase recombination target) site
Chromosome UN
Common name No Data
Symbol description No Data
4 Symbol GH
Symbol name Growth hormone polyA (Bovine)
Chromosome UN
Common name No Data
Symbol description No Data
5 Symbol Gt(ROSA)26Sor
Symbol name gene trap ROSA 26, Philippe Soriano
Chromosome UN
Common name No Data
Symbol description No Data
6 Symbol WPRE
Symbol name Woodchuck hepatitis virus posy-transcriptional regulatory element (WPRE)
Chromosome UN
Common name No Data
Symbol description No Data
7 Symbol loxP
Symbol name phage P1 loxP
Chromosome UN
Common name No Data
Symbol description No Data
Promoter CAG promoter (CMV-IE enhancer, chicken beta-actin promoter, rabbit beta-globin genomic DNA)
8 Symbol No Data
Symbol name C1V1 (Chlamydomonas reinhardtii, Volvox carteri)
Chromosome UN
Common name No Data
Symbol description No Data
References No Data

Research applications Cre/loxP system,
FLP/frt system,
Fluorescent Proteins/lacZ System
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested.
(後日指定)
In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested.
The availability of the BIOLOGICAL RESOURCE is limited to a RECIPIENT of a not-for profit institution for a not-for-profit research. The RECIPIENT of BIOLOGICAL resource shall obtain a prior written consent on use of it from the DEPOSITOR Dr. Itaru Imayoshi (E-mail: iimayosh@virus.kyoto-u.ac.jp). (No approval form (Form D) is necessary). The RECIPIENT of BIOLOGICAL RESOURCE must obtain a prior written consent on use of it from the DEVELOPER of the C1V1·ChR2(SSFO) (Dr. Karl Deisseroth, http://web.stanford.edu/group/dlab/optogenetics/request_dna.html).
Additional information
1 GFP Transfer License (Japanese / English)
Please fill in the Schedule A, and submit two signed copies to us together with two signed copies of RIKEN BRC’s MTA. Please also read Schedule B.
Depositor Imayoshi, Itaru (Institute for Virus Research, Kyoto University) Imayoshi, Itaru
Strain Status /
Availability
(Expected delivery)


Sperm
Cryopreserved sperm : Within 1 month
Recovered litters from cryopreserved sperm : 2-4 months

RBRC06811, C57BL/6N-Atp6v1g2<em1Rbrc>

RBRC No. RBRC06811
Type CRISPR/Cas9
Species Mus musculus
Strain name C57BL/6N-Atp6v1g2<em1Rbrc>
Former Common name No Data
H-2 Haplotype No Data
Background strain C57BL/6NTac
Appearance
1 Appearance No Data
Genotype No Data
Strain description No Data
Health Report
Gene Details
Promoter No Data
1 Symbol Atp6v1g2
Symbol name ATPase, H+ transporting, lysosomal V1 subunit G2
Chromosome 17
Common name No Data
Symbol description No Data
References No Data

Research applications No Data
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
The RECIPIENT should acknowledge RIKEN BRC and the International Mouse Phenotyping Consortium for creating and providing of the knockout mice.
Additional information
1 No Data
Depositor RIKEN, BioResource Center
Strain Status /
Availability
(Expected delivery)


Sperm
Cryopreserved sperm : Within 1 month
Recovered litters from cryopreserved sperm : 2-4 months

RBRC09251, CHe.STS-(D4Mit163-D4Mit31)

RBRC No. RBRC09251
Type Congenic
Species Mus musculus
Strain name CHe.STS-(D4Mit163-D4Mit31)
Former Common name C.S163-31, BALB-163-31
H-2 Haplotype No Data
Background strain No Data
Appearance
1 Appearance No Data
Genotype No Data
Strain development Developed by Nobuko Mori, Osaka Prefecture University.
Strain description BALB/cHeA congenic strain carries a genomic region that contributes to radiation induced thymic lymphomas resistance phenotype of STS/A. C.S163-31 line (RBRC09251), C.S39-86 line (RBRC09252).
Colony maintenance Homozygote x Homozygote
Health Report
Gene Details
Promoter No Data
1 Symbol No Data
Symbol name No Data
Chromosome No Data
Common name No Data
Symbol description No Data
References http://dx.doi.org/10.5772/55159

Research applications Cancer Research
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
The availability of the BIOLOGICAL RESOURCE is limited to a RECIPIENT of a not-for profit institution for a not-for-profit research.
Additional information
1 No Data
Depositor Mori, Nobuko (Osaka Prefecture University) Mori, Nobuko
Strain Status /
Availability
(Expected delivery)


Frozen
Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months

Sperm
Cryopreserved sperm : Within 1 month
Recovered litters from cryopreserved sperm : 2-4 months

RBRC09296, B10.A/SgSnSlcNiid

RBRC No. RBRC09296
Type Inbred
Species Mus musculus
Strain name B10.A/SgSnSlcNiid
Former Common name B10.A Niid
H-2 Haplotype No Data
Background strain No Data
Appearance
1 Appearance No Data
Genotype No Data
Strain description No Data
Health Report
BRC facility Health Report in the last year and a half

Examination Date Room Rack
May 14, 2018 2-検 F
Mar 12, 2018 2-検 F
Jan 15, 2018 2-検 F
Nov 13, 2017 2-検 F
Sep 11, 2017 2-検 F
Jul 10, 2017 2-検 F
May 15, 2017 2-検 F
Mar 13, 2017 2-検 F

Gene Details
Promoter No Data
1 Symbol Naip5
Symbol name NLR family, apoptosis inhibitory protein 5
Chromosome 13
Common name Birc1e
Symbol description No Data
2 Symbol Lgn2
Symbol name Legionella, susceptiblility 2
Chromosome 13
Common name No Data
Symbol description No Data
References No Data

Research applications Immunology and Inflammation Research
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested.
Additional information
1 No Data
Depositor Ohnishi, Makoto (National Institute of Infectious Diseases) Ohnishi, Makoto
Strain Status /
Availability
(Expected delivery)


Frozen
Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months

Sperm
Cryopreserved sperm : Within 1 month
Recovered litters from cryopreserved sperm : 2-4 months

RBRC09313, Gpr98<tm1>

RBRC No. RBRC09313
Type Targeted MutationCartagena
Species Mus musculus
Strain name Gpr98<tm1>
Former Common name No Data
H-2 Haplotype No Data
ES cell line E14.1 [129P2/OlaHsd]
Background strain No Data
Appearance
1 Appearance No Data
Genotype No Data
Strain description No Data
Health Report No Data
Gene Details
Promoter No Data
1 Symbol Adgrv1
Symbol name adhesion G protein-coupled receptor V1
Chromosome 13
Common name Gpr98, Mass1, Mgr1, Neurepin, VLGR1
Symbol description No Data
Promoter mouse phosphoglycerate kinase promoter (PGK promoter)
2 Symbol neo
Symbol name neomycin resistance gene (E. coli)
Chromosome 13
Common name No Data
Symbol description No Data
References No Data

Research applications No Data
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested.
J. Neurochem., 92, 191-202 (2005).
In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested.
The availability of the BIOLOGICAL RESOURCE is limited to a RECIPIENT of a not-for profit institution for a not-for-profit research.
Additional information
1 No Data
Depositor Sato, Makoto (University of Fukui) Sato, Makoto
Strain Status /
Availability
(Expected delivery)


Preparing for distribution
Preparing for distribution
(Please note that it may take more than 6 months to make arrangements to distribute.)

Frozen
Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months