|Type||Wild-derived Inbred and Spontaneous Mutation|
|Species||Mus musculus molossinus|
|Former Common name||hyperlipidemia|
|H-2 Haplotype||No Data|
|Background strain||KOR [Mus musculus molossinus]|
|1||Appearance||white belly agouti|
|Strain development||Spontaneous mutation arose in KOR wild-derived mouse colony. The mutant mice were maintained by sibling mating.|
|Strain description||SHL, spontaneously hyperlipidemia mutant mice. Spontaneous mutation arose in KOR mouse colony derived from Japanese wild-mice (Mus musculus molossius). Homozygous mutant mice show increased circulating cholesterol level. Homozygous mutant mice are viable and fertile (before onset of xanthoma). Females of homozygote show lower reproductive performance.|
|Symbol name||apolipoprotein E|
|Symbol description||No Data|
|References||The Lipid, 13, 318-324 (2002).
J Atheroscler Thromb. 2001;8(3):71-9.
Mamm Genome. 1999 Apr;10(4):352-7.
|Research applications||Hematological Research|
|Specific Term and Conditions||The following terms and conditions will be requested by the DEPOSITOR.
The RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR.
In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested.
In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested.
The RECIPIENT shall use the BIOLOGICAL RESOURCE only for academic research for the purpose of publishing the research results.
|1||Mouse of the Month Jan 2006|
|Depositor||Matsushima, Yoshibumi (Saitama Cancer Center)|
|Strain Status /