RBRC00134, C57BL/6-Lyst<bg-J>/StmRbrc

RBRC No. RBRC00134
Type Spontaneous Mutation Congenic wks
Species Mus musculus
Strain name C57BL/6-Lyst<bg-J>/StmRbrc
Former Common name C57BL/6-bg/bg
H-2 Haplotype b
Background strain C57BL/6J
1 Appearance light black
Genotype aaBBCC;bgJ/bgJ
Strain development Jackson Laboratory – Aichi Cancer Center Research Institute (1973?) – Saitama Cancer Center (1977, F16).
Strain description Beige spontaneous mutant mice. Homozygous mutant mice snow a phenotype similar to human Chediak-Higashi syndrome.
Colony maintenance Homozygote x Homozygote
Health Report
Gene Details
Promoter No Data
1 Symbol Lyst
Symbol name lysosomal trafficking regulator
Chromosome 13
Common name beige, bg, D13Sfk13
Symbol description No Data
References Nature. 1996 Jul 18;382(6588):262-5.

Identification of the homologous beige and Chediak-Higashi syndrome genes.
Research applications Dermatology Research,
Hematological Research,
Immunology and Inflammation Research,
Internal/Organ Research,
Metabolism Research,
Mouse Models for Human Disease
Specific Term and Conditions No specific terms and conditions. (The DEPOSITOR waives its own rights under any patents, intellectual property, or other proprietary rights with respect to the results to be obtained by use of the BIOLOGICAL RESOURCE.)
Additional information
1 No Data
Depositor Shisa, Hayase (Saitama Cancer Center) Shisa, Hayase
Strain Status /
(Expected delivery)

Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months