RBRC00165, B6.129S4-Zic2<tm1Jaru>/JaruRbrc

RBRC No. RBRC00165
Type Targeted MutationCartagena
Species Mus musculus
Strain name B6.129S4-Zic2<tm1Jaru>/JaruRbrc
Former Common name C57BL/6N-Kd(Zic2), Zic2 Knockdown mouse
H-2 Haplotype No Data
Donor strain 129S4/SvJae via J1 ES cell line
Background strain C57BL/6N
Appearance
1 Appearance black
Genotype No Data
Strain description No Data
Health Report No Data
Gene Details
Promoter No Data
1 Symbol Zic2
Symbol name zinc finger protein of the cerebellum 2
Chromosome 14
Common name No Data
Symbol description No Data
Promoter mouse phosphoglycerate kinase promoter (PGK promoter)
2 Symbol neo
Symbol name neomycin resistance gene (E. coli)
Chromosome 14
Common name neo; neomycin;
Symbol description No Data
References J Neurosci. 2002 Jan 1;22(1):218-25.
Proc Natl Acad Sci U S A. 2000 Feb 15;97(4):1618-23.

Research applications Neurobiology Research
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
The RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR.
In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested.
Proc. Natl. Acad. Sci. USA, 97, 1618-1623 (2000).
Additional information
1 Lab HP
Depositor Aruga, Jun (RIKEN Center for Brain Science) Aruga, Jun
Strain Status /
Availability
(Expected delivery)


Frozen
Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months

Sperm
Cryopreserved sperm : Within 1 month
Recovered litters from cryopreserved sperm : 2-4 months
BRC mice in Publications
Title Journal
(PMID)
Author
Zic2 promotes axonal divergence at the optic chiasm midline by EphB1-dependent and -independent mechanisms. Development.135(10): 1833-41 (2008).(18417618)
Garc a-Frigola C, Carreres MI, Vegar C, Mason C, Herrera E.
Zic2 regulates the expression of Sert to modulate eye-specific refinement at the visual targets. EMBO J.29(18): 3170-83 (2010).(20676059)
Garc a-Frigola C, Herrera E.
Shh/Boc signaling is required for sustained generation of ipsilateral projecting ganglion cells in the mouse retina. J Neurosci.33(20): 8596-607 (2013).(23678105)
S nchez-Arrones L, Nieto-Lopez F, S nchez-Camacho C, Carreres MI, Herrera E, Okada A, Bovolenta P.