RBRC00432, RLC/Stm

RBRC No. RBRC00432
Type Spontaneous Mutation 14wks,♂
Species Mus musculus
Strain name RLC/Stm
Former Common name No Data
H-2 Haplotype No Data
Background strain RLC/Stm
Appearance
1 Appearance albino
Genotype No Data
Strain development Spontaneous mutation originally arose in CXSN/A strain. The mutant mice were bred with a BALB/cHeA and then maintained by inbreeding.
Strain description rlc, Rupture of Lens Cataract. Spontaneous recessive mutation arose in CXSN/A mice. The mutation as a deletion of 27 bp at the end of 15th of Dock5 gene.
Health Report
Gene Details
Promoter No Data
1 Symbol Dock5
Symbol name dedicator of cytokinesis 5
Chromosome 14
Common name lr2
Symbol description No Data
References Exp Eye Res. 1997 Jan;64(1):107-13.
Genomics. 1996 Sep 15;36(3):553-4.
Graefes Arch Clin Exp Ophthalmol. 2000 Dec;238(12):970-8.

Rupture of lens cataract: a novel hereditary recessive cataract model in the mouse.
Rupture of lens cataract: a novel hereditary recessive cataract model in the mouse.
Rupture of lens cataract: a novel hereditary recessive cataract model in the mouse.
Research applications Mouse Models for Human Disease,
Sensorineural Research
Specific Term and Conditions No specific terms and conditions. (The DEPOSITOR waives its own rights under any patents, intellectual property, or other proprietary rights with respect to the results to be obtained by use of the BIOLOGICAL RESOURCE.)
Additional information
1 No Data
Depositor Matsushima, Yoshibumi (Saitama Cancer Center) Matsushima, Yoshibumi
Strain Status /
Availability
(Expected delivery)


Frozen
Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months
BRC mice in Publications
Title Journal
(PMID)
Author
Pre-B lymphomas in SL/Kh mice: a multifactorial disease model. Cancer Sci.94(10): 847-850 (2003).(14556656)
Hiai H, Tsuruyama T, Yamada Y.