RBRC00458, B6.129P2-Cdkn1b<tm1Kin>

RBRC No. RBRC00458
Type Targeted MutationCartagena
Species Mus musculus
Strain name B6.129P2-Cdkn1b<tm1Kin>
Former Common name B6.129P2-Cdkn1b; p27 Knockout mice
H-2 Haplotype No Data
ES cell line E14 [129P2/OlaHsd]
Background strain C57BL/6JJcl
1 Appearance No Data
Genotype No Data
Strain development Developed by Keiko Nakayama and Kei-ichi Nakayama, Howard Hughes Medical Institute, Washington University School of Medicine in 1996. E14 ES cells were used to generate the mutant mice. The mutant mice were backcrossed to C57BL/6.
Strain description p27 (Cdkn1b) gene knockout mice. A 2.5 kb region containing exons 1 and 2 was replaced with a PGK-neo cassette.
Colony maintenance Heterozygote x Wild-type [C57BL/6JJcl]
Health Report No Data
Gene Details
Promoter No Data
1 Symbol Cdkn1b
Symbol name cyclin-dependent kinase inhibitor 1B
Chromosome 6
Common name Kip1, p27, p27Kip1
Symbol description No Data
Promoter mouse phosphoglycerate kinase promoter (PGK promoter)
2 Symbol neo
Symbol name neomycin resistance gene (E. coli)
Chromosome 6
Common name neo; neomycin;
Symbol description No Data
References No Data

Research applications No Data
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
The RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR.
The RECIPIENT agrees to use this BIOLOGICAL RESOURCE as a collaboration with the DEPOSITOR.
Additional information
1 Lab HP
2 Genotyping protocol <PCR>
Depositor Nakayama, Keiichi (Medical institute of bioregulation, Kyushu University) Nakayama, Keiichi
Strain Status /
(Expected delivery)

Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months

Cryopreserved sperm : Within 1 month
Recovered litters from cryopreserved sperm : 2-4 months