RBRC01059, NC

RBRC No. RBRC01059
Type Inbred
Species Mus musculus
Strain name NC
Former Common name No Data
H-2 Haplotype No Data
Background strain No Data
1 Appearance agouti brown
Genotype A/A b/b C/C D/D S/S
Strain development Developed by Dr. Kyoji Kondo at Nagoya University, School of Agriculture. Derived from a cinnamon coat color colony of Japanese fancy mice (Nishiki-Nezumi).
Strain description NC/Nga mice were originated from Japanese fancy mice (Nishiki-Nezumi) and were established as a inbred strain in 1955. NC/Nga mice develop skin lesions similar to atopic dermatitis when kept under conventional environment, but not under specific pathogen -free environment as specific pathogen-free animals. They also show a high susceptibility to X-irradiation and anaphylactic shock from ovalbumin. Developed by Dr. Kyoji Kondo at Nagoya University.
Colony maintenance Sibling Mating
Health Report
Gene Details
Promoter No Data
1 Symbol Derm1
Symbol name dermititis 1
Chromosome 9
Common name No Data
Symbol description No Data
References JIkken Doubutsu, 6, 107-112 (1957).

Research applications Dermatology Research
Specific Term and Conditions No specific terms and conditions. (The DEPOSITOR waives its own rights under any patents, intellectual property, or other proprietary rights with respect to the results to be obtained by use of the BIOLOGICAL RESOURCE.)
Additional information
1 No Data
Depositor Namikawa, Takao (Nagoya University) Namikawa, Takao
Strain Status /
(Expected delivery)

Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months
BRC mice in Publications
Title Journal
Antidermatitic perspective of hydrocortisone as chitosan nanocarriers: An ex vivo and in vivo assessment using an NC/Nga mouse model. J Pharm Sci. (2013).(23303620)
Hussain Z, Katas H, Amin MC, Kumulosasi E, Sahudin S.
Self-assembled polymeric nanoparticles for percutaneous co-delivery of hydrocortisone/hydroxytyrosol: An ex vivo and in vivo study using an NC/Nga mouse model. Int J Pharm. (2013).(23337632)
Hussain Z, Katas H, Mohd Amin MC, Kumolosasi E, Buang F, Sahudin S.
Efficient immuno-modulation of TH1/TH2 biomarkers in 2,4-dinitrofluorobenzene-induced atopic dermatitis: nanocarrier-mediated transcutaneous co-delivery of anti-inflammatory and antioxidant drugs. PLoS One.9(11) e113143: e113143 (2014).(25396426)
Hussain Z, Katas H, Mohd Amin MC, Kumolosasi E.
Development of Eczema Vaccinatum in Atopic Mouse Models and Efficacy of MVA Vaccination against Lethal Poxviral Infection. PLoS One.9(12) e114374: e114374 (2014).(25486419)
Knitlova J, Hajkova V, Voska L, Elsterova J, Obrova B, Melkova Z.
Pseudolaric acid B attenuates atopic dermatitis-like skin lesions by inhibiting interleukin-17-induced inflammation. Sci Rep7(1): 7918 (2017).(28801611)
Yang Z, Liu M, Wang W, Wang Y, Cao B, Gao Y, Chen H, Li T.
Hyaluronic Acid Decorated Tacrolimus-Loaded Nanoparticles: Efficient Approach to Maximize Dermal Targeting and Anti-dermatitis Efficacy. Carbohydr. Polym. (2018).(30007638)
F Zhuo, MAS Abourehab, Z Hussain.