RBRC01080, B6.129S-Drd1a<tm1Mok>

RBRC No. RBRC01080
Type Targeted MutationCartagena wks
Species Mus musculus
Strain name B6.129S-Drd1a<tm1Mok>
Former Common name D1R KO, B6-D1R KO
H-2 Haplotype No Data
ES cell line CCE/EK.CCE [129S/SvEv-Gpi1]
Background strain C57BL/6JJcl
Appearance
1 Appearance black
Genotype a/a B/B C/C
Strain development Developed by Motoya Katsuki, National Institutes of Natural Sciences.
Strain description D1R (Ded1a) gene knockout mice.
Colony maintenance Heterozygote x Wild-type [C57BL/6JJcl]
Health Report
Gene Details
Promoter No Data
1 Symbol Drd1
Symbol name dopamine receptor D1A
Chromosome 13
Common name C030036C15Rik, D1 receptor, Drd-1, Drd1, Gpcr15
Symbol description No Data
Promoter herpes simplex virus thymidine kinase promoter (HSV tk promoter)
2 Symbol neo
Symbol name neomycin resistance gene (E. coli)
Chromosome 13
Common name neo; neomycin;
Symbol description No Data
Promoter mouse phosphoglycerate kinase promoter (PGK promoter)
3 Symbol Ecogpt
Symbol name E.coli xanthine phosphoribosyltransferase
Chromosome 13
Common name No Data
Symbol description No Data
References

Research applications No Data
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested.
J. Neuroscience, 28(50), 13390-13400 (2008).
In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to Dr. Motoya Katsuki is requested. The RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE.
Additional information
1 Mouse of the Month Oct 2009
2 Genotyping protocol <PCR>
Depositor Sasaoka, Toshikuni (Niigata university) Sasaoka, Toshikuni
Strain Status /
Availability
(Expected delivery)


Frozen
Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months

Sperm
Cryopreserved sperm : Within 1 month
Recovered litters from cryopreserved sperm : 2-4 months
BRC mice in Publications
Title Journal
(PMID)
Author
Hippocampal place cell responses to distal and proximal cue manipulations in dopamine D2 receptor-knockout mice. Brain Res. (2014).(24747614)
Nguyen CL, Tran AH, Matsumoto J, Hori E, Uwano T, Ono T, Nishijo H.
Predominant D1 Receptors Involvement in the Over-expression of CART Peptides after Repeated Cocaine Administration. Korean J. Physiol. Pharmacol.19(2): 89-97 (2015).(25729269)
Hu Z, Oh EH, Chung YB, Hong JT, Oh KW.
Dopamine D1 Receptor Immunoreactivity on Fine Processes of GFAP-Positive Astrocytes in the Substantia Nigra Pars Reticulata of Adult Mouse. Front Neuroanat11: 3 (2017).(28203148)
Nagatomo K, Suga S, Saitoh M, Kogawa M, Kobayashi K, Yamamoto Y, Yamada K.