RBRC01088, B6.129S-Hras<tm1Mok>/MokRbrc

RBRC No. RBRC01088
Type Targeted MutationCartagena
Species Mus musculus
Strain name B6.129S-Hras<tm1Mok>/MokRbrc
Former Common name H-ras KO, B6-Hras KO, B6.129S-Hras1<tm1Mok>
H-2 Haplotype No Data
ES cell line CCE/EK.CCE [129S/SvEv-Gpi1]
Background strain C57BL/6JJcl
Appearance
1 Appearance No Data
Genotype No Data
Strain development Developed by Motoya Katsuki, National Institutes of Natural Sciences (Institute of Medical Science, University of Tokyo).
Strain description Hras gene knockout mice.
Colony maintenance Heterozygote x Wild-type [C57BL/6JJcl]
Health Report
Gene Details
Promoter No Data
1 Symbol Hras
Symbol name Harvey rat sarcoma virus oncogene
Chromosome 7
Common name c-H-ras, c-rasHa, H-ras, Ha-ras, Harvey-ras, Hras-1, ras
Symbol description No Data
Promoter herpes simplex virus thymidine kinase promoter (HSV tk promoter)
2 Symbol neo
Symbol name neomycin resistance gene (E. coli)
Chromosome 7
Common name neo; neomycin;
Symbol description No Data
References Oncogene. 2000 Jun 15;19(26):2951-6.

Targeted deletion of the H-ras gene decreases tumor formation in mouse skin carcinogenesis.
Research applications Cancer Research
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested.
Oncogene. 19, 2951-2956 (2000) .
In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to Dr. Motoya Katsuki is requested. The RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE.
Additional information
1 No Data
2 Genotyping protocol <PCR>
Depositor Sasaoka, Toshikuni (Niigata university) Sasaoka, Toshikuni
Strain Status /
Availability
(Expected delivery)


Frozen
Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months

Sperm
Cryopreserved sperm : Within 1 month
Recovered litters from cryopreserved sperm : 2-4 months