RBRC01100, B6.Cg-Tg(Ovgp1-TAg)1Imiy

RBRC No. RBRC01100
Type TransgeneCartagena wks
Species Mus musculus
Strain name B6.Cg-Tg(Ovgp1-TAg)1Imiy
Former Common name B6.Cg-Tg(Ovgp1-TAg)1Imiy; mogP-Taq Transgenic mouse; Mouse Transgenic for Murine Oviduct-Specific Glycoprotein Promoter-Driven Simian Virus 40 Large T-Antigen (mogp-Taq Transgenic Mouse)
H-2 Haplotype No Data
Background strain C57BL/6
Appearance
1 Appearance No Data
Genotype No Data
Strain development Developed by Ichiro Miyoshi and Noriyuki Kasai, Tohoku University Graduate School of Medicine in 2001. The transgene was injected into the pronuclei of B6D2F2 fertilized eggs. The mutant mice were crossed to C57BL/6.
Strain description mogp-Tag transgenic mice, expressing a simian virus 40 large T antigen (Tag) under the control of murine oviduct specific glycoprotein promoter (a 2.2-kb segment of the 5'-flanking sequence). Tg females develop severe uterine tumors by 6 weeks of age. Average life span of Tg males is around 6 months.
Colony maintenance Carrier (male) x Noncarrier (female) [C57BL/6JJcl]
Health Report No Data
Gene Details
Promoter No Data
1 Symbol No Data
Symbol name rabbit beta-globin poly A
Chromosome UN
Common name No Data
Symbol description No Data
Promoter Murine Oviduct-Specific Glycoprotein Promoter, rabbit beta-globin poly A
2 Symbol TAg
Symbol name SV40 Large T-Antigen
Chromosome UN
Common name No Data
Symbol description No Data
References Mol Reprod Dev. 2002 Oct;63(2):168-76.

Mouse transgenic for murine oviduct-specific glycoprotein promoter-driven simian virus 40 large T-antigen: tumor formation and its hormonal regulation.
Research applications Cancer Research,
Reproductive Biology Research
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
The RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR.
In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested.
Molecular Reproduction and Development, 63, 168-176 (2002).
The DEPOSITOR should be a co-author in articles when the RECIPIENTs publish their data using these mice for 2 year after provided to the RIKEN BRC.
Additional information
1 No Data
2 Genotyping protocol <PCR>
Depositor Kasai, Noriyuki (Tohoku University) Kasai, Noriyuki
Strain Status /
Availability
(Expected delivery)


Frozen
Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months

Sperm
Cryopreserved sperm : Within 1 month
Recovered litters from cryopreserved sperm : 2-4 months