RBRC01221, SM/J

RBRC No. RBRC01221
Type Inbred wks
Species Mus musculus
Strain name SM/J
Former Common name No Data
H-2 Haplotype No Data
Background strain SM
1 Appearance white-bellied agouti
Genotype A/a
2 Appearance black
Genotype a/a
Strain development Developed by MacArthur in 1939. The SM/J strain was produced by crossing seven inbred strains including DBA and selecting for small body size. This strain was introduced to National Institute of Genetics from the Jackson laboratory in 1985, subsequently maintained by Dr. Masahiko Nishimura at Hamamatsu University School of Medicine, and then Nagoya University.
Strain description The SM/J strain is segregating inbred strain for the agouti alleles white-bellied agouti (A<w>) and black (a). Developed by MacArthur in 1939. These mice are susceptible to diet-induced atherosclerosis and obesity without diabetes. The body size is small at birth and weaning, but attain a normal body weight as the animals mature.
Colony maintenance Sibling mating (white-bellied agouti x black)
Health Report
Gene Details
Promoter No Data
1 Symbol No Data
Symbol name No Data
Chromosome No Data
Common name No Data
Symbol description No Data
References Biosci Biotechnol Biochem. 2006 Mar;70(3):677-83.
Diabetes. 2003 Jan;52(1):180-6.
Diabetologia. 2006 Mar;49(3):486-95. Epub 2006 Jan 31.
Immunogenetics. 2002 Feb;53(10-11):925-9. Epub 2002 Jan 29.
J Lipid Res. 2007 Sep;48(9):2039-46. Epub 2007 Jun 26.

Research applications Genetics Research
Specific Term and Conditions No specific terms and conditions. (The DEPOSITOR waives its own rights under any patents, intellectual property, or other proprietary rights with respect to the results to be obtained by use of the BIOLOGICAL RESOURCE.)
Additional information
1 No Data
Depositor Nishimura, Masahiko (Nagoya University) Nishimura, Masahiko
Strain Status /
(Expected delivery)

Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months
BRC mice in Publications
Title Journal
Major quantitative trait locus on chromosome 2 for glucose tolerance in diabetic SMXA-5 mouse established from non-diabetic SM/J and A/J strains. Diabetologia.49(3): 486-95 (2006).(16447060)
Kobayashi M, Io F, Kawai T, Kumazawa M, Ikegami H, Nishimura M, Ohno T, Horio F.
Serum adiponectin concentration: its correlation with diabetes-related traits and quantitative trait loci analysis in mouse SMXA recombinant inbred strains. Biosci Biotechnol Biochem.70(3): 677-83 (2006).(16556985)
Kobayashi M, Ohno T, Kawada T, Ikegami H, Nishimura M, Horio F.
Searching for genetic factors of fatty liver in SMXA-5 mice by quantitative trait loci analysis under a high-fat diet. J Lipid Res.48(9): 2039-46 (2007).(17595448)
Kumazawa M, Kobayashi M, Io F, Kawai T, Nishimura M, Ohno T, Horio F.
Low expression of Neu2 sialidase in the thymus of SM/J mice-existence of neuraminidase positive cells “Neu-medullocyte” in the murine thymus. Glycoconj. J.25(8): 787-96 (2008).(18553168)
Kijimoto-Ochiai S, Koda T, Suwama T, Matsukawa H, Fujii M, Tomobe K, Nishimura M.
NEU1 sialidase exists on the cell surface of the mouse thymocyte and CD5 is a natural substrate for it. Glycobiology28(5): 306-317 (2018).(29897583)
Shigeko Kijimoto-Ochiai, Tokuko Matsumoto-Mizuno, Daisuke Kamimura, Masaaki Murakami, Miwako Kobayashi, Ichiro Matsuoka, Hiroshi Ochiai, Hideharu Ishida, Makoto Kiso, Keiko Kamimura, Toshiaki Koda.