|Former Common name||No Data|
|H-2 Haplotype||No Data|
|Genotype||a/a B/B C/C|
|Strain development||Developed by Kazuto Kobayashi, Fukushima Medical University School of Medicine in 1998. The transgene was injected into the pronuclei of B6D2F2 fertilized eggs. The transgenic mice were backcrossed to C57BL/6J.|
|Strain description||These transgenic mice express Cre recombinase gene under the control of the human dopamin beta hydroxylase (DBH) gene promoter. This strain can be used to make an inducible knock-out by crossing with the other genetically-engineered mice that have a loxP site-flanked sequence of interest. The recombination occurs in typical noradrenergic and adrenergic cell groups as well as in transient catecholaminergic cell types. Line 6-8 (RBRC01297), Line 9-9 (RBRC01492).|
|Colony maintenance||Carrier x Noncarrier [C57BL/6JJcl]|
|Promoter||human dopamine beta-hydroxylase (DBH) promoter, rabbit beta-globin intron, rabbit beta-globin poly A, SV40 early gene poly A|
|Symbol name||Phage P1 Cre recombinase|
|Common name||No Data|
|Symbol description||No Data|
|References||J Neurosci Res. 2004 Oct 1;78(1):7-15.
Fate of transient catecholaminergic cell types revealed by site-specific recombination in transgenic mice.
|Research applications||Cell Biology Research,
|Specific Term and Conditions||The following terms and conditions will be requested by the DEPOSITOR.
The RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR.
In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested.
J. Neursci. Res., 78, 7-15 (2004).
In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested.
|1||Lab HP (Japanese)|
|2||Mouse of the Month Jun 2005
Mouse of the Month June 2006
|3||Genotyping protocol <PCR>|
|Depositor||Kobayashi, Kazuto (Fukushima Medical University)|
|Strain Status /