Strain Information | |
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Image | |
BRC No. | RBRC01528 |
Type | Transgene |
Species | Mus musculus |
Strain name | B6.Cg-Tg(NP-IL2R/GFP)3-10Koba/KobaRbrc |
Former Common name | NP-IL2R/3-10 |
H-2 Haplotype | |
ES Cell line | |
Background strain | C57BL/6JJcl |
Appearance | |
Strain development | Developed by Dr. Kazuto Kobayashi, Fukushima Medical University School of Medicine in 1998. The transgene was injected into the pronuclei of B6D2F2 fertilized eggs. The transgenic mice were backcrossed to C57BL/6J. |
Strain description | The transgene contains mouse neuropsin gene promoter (BAC clone), human interleukin-2 receptor alpha-subunit/GFP. Subthalamic neurons are disrupted by a recombinant immunotoxin. |
Colony maintenance | |
References | J. Neurosci., 25, 7743-7753 (2005). 16120775 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter GFPGreen Fluorescent Protein (Aequorea victoria)UN Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter IL2RAInterleukin-2 receptor α-subunit (human)UNIL2RAmouse neropsin (NP) promoter, rabbit beta-globin intron,rabbit beta-globin poly A, SV40 early gene poly A |
Ordering Information | |
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Donor DNA | mouse neropsin (NP) promoter, rabbit beta-globin intron, human Interleukin-2 receptor α-subunit cDNA, rabbit beta-globin poly A, SV40 early gene poly A, jellyfish GFP cDNA |
Research application | Fluorescent Proteins/lacZ System |
Specific Term and Conditions | The RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. J. Neurosci., 25 (34) 7743-7753 (2005). In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested. |
Depositor | Kazuto Kobayashi (Fukushima Medical University) |
Strain Status | Frozen embryos |
Strain Availability | Recovered litters from cryopreserved embryos (2 to 4 months) Cryopreserved embryos (within 1 month) |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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No Data |