RBRC01952, B6;129S2-Lats1<tm1Noj>

RBRC No. RBRC01952
Type Targeted MutationCartagena wks
Species Mus musculus
Strain name B6;129S2-Lats1<tm1Noj>
Former Common name Lats1 heterozygous (He) mouse
H-2 Haplotype No Data
ES cell line D3 [129S2/SvPas]
Background strain No Data
Appearance
1 Appearance No Data
Genotype No Data
Strain development Developed by Norikazu Yabuta and Hiroshi Nojima, Research Institute for Microbial Diseases, Osaka University in 2004. D3 ES cells were used. The mutant mice were crossed to C57BL/6.
Strain description Lats1 gene knockout mice (deltaN type). Exon 1 containing a translation initiation codon was replaced with a PGK-neo cassette. Homozygous mutant mice are small. Homozygous mutant females cannot nurse pups due to lacking mammae.
Colony maintenance Heterozygote x Wild-type [C57BL/6NCrSlc]
Health Report No Data
Gene Details
Promoter No Data
1 Symbol Lats1
Symbol name large tumor suppressor
Chromosome 10
Common name No Data
Symbol description No Data
Promoter mouse phosphoglycerate kinase promoter (PGK promoter)
2 Symbol neo
Symbol name neomycin resistance gene (E. coli)
Chromosome 10
Common name neo; neomycin;
Symbol description No Data
References

Research applications Cell Biology Research
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
The RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR.
In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested.
J CellSci., 126, 508-520 (2013).
The RECIPIENT agrees to use of this BIOLOGICAL RESOURCE as a collaboration with the DEPOSITOR.
Additional information
1 No Data
Depositor Nojima, Hiroshi (Osaka university) Nojima, Hiroshi
Strain Status /
Availability
(Expected delivery)


Frozen
Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months

Sperm
Cryopreserved sperm : Within 1 month
Recovered litters from cryopreserved sperm : 2-4 months