RBRC01958, B6.Cg-Ahnak<tm1Jtak>

RBRC No. RBRC01958
Type Targeted Mutation CongenicCartagena wks
Species Mus musculus
Strain name B6.Cg-Ahnak<tm1Jtak>
Former Common name Ahnaktm1Tak
H-2 Haplotype No Data
Background strain No Data
1 Appearance black
Genotype a/a B/B C/C
Strain development Developed by Dr. Junji Takeda at Osaka University in 2001.
Strain description AHNAK/Desmoyokin is a ubiquitous protein expressed in a variety of cell type, distributes mainly on the cell membranes, suggesting that this gene plays a role in cell-cell adhesion. Homozygous mutant mice are viable and fertile, and show no overt abnormalities.
Colony maintenance Backcross to C57BL/6J
Health Report
Gene Details
Promoter No Data
1 Symbol Ahnak
Symbol name AHNAK nucleoprotein (demoyokin)
Chromosome 19
Common name 1110004P15Rik, 2310047C17Rik, DY6
Symbol description No Data
2 Symbol neo
Symbol name neomycin resistance gene (E. coli)
Chromosome 19
Common name neo; neomycin;
Symbol description No Data
3 Symbol loxP
Symbol name phage P1 loxP
Chromosome 19
Common name No Data
Symbol description No Data
References J Invest Dermatol 2004 Oct;123(4):700-7.

Ahnak/Desmoyokin is dispensable for proliferation, differentiation, and maintenance of integrity in mouse epidermis.
Research applications No Data
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
The RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR.
In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested.
J Invest Dermatol, 123, 700-707 (2004).
RECIPIENT which wants to use the BIOLOGICAL RESOURCE for the purpose other than education or not-for-profit research is requested to enter into a Material Transfer Agreement with Osaka University.
Additional information
1 Takeda Lab HP
2 Genotyping protocol <PCR>
Depositor Takeda, Junji (Osaka University) Takeda, Junji
Strain Status /
(Expected delivery)

Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months

Cryopreserved sperm : Within 1 month
Recovered litters from cryopreserved sperm : 2-4 months
BRC mice in Publications
Title Journal
Giant scaffolding protein AHNAK1 interacts with beta-dystroglycan and controls motility and mechanical properties of schwann cells. Glia. (2014).(24796807)
von Boxberg Y, Soares S, F r ol S, Fodil R, Bartolami S, Taxi J, Tricaud N, Nothias F.