RBRC02106, B6.129-Lefty1<tm1Hmd>

RBRC No. RBRC02106
Type Targeted MutationCartagena wks
Species Mus musculus
Strain name B6.129-Lefty1<tm1Hmd>
Former Common name lefty 1 null KO
H-2 Haplotype No Data
ES cell line E14 [129P2/OlaHsd]
Background strain No Data
Appearance
1 Appearance No Data
Genotype No Data
Strain description No Data
Health Report
Gene Details
Promoter No Data
1 Symbol Lefty1
Symbol name left right determination factor 1
Chromosome 1
Common name Leftb, lefty-1, Stra3
Symbol description No Data
Promoter SV40 and herpes simplex virus thymidine kinase promoter (HSV tk promoter)
2 Symbol neo
Symbol name neomycin resistance gene (E. coli)
Chromosome 1
Common name neo; neomycin;
Symbol description No Data
References Cell. 1998 Aug 7;94(3):287-97.

lefty-1 is required for left-right determination as a regulator of lefty-2 and nodal.
Research applications Developmental Biology Research
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
The RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR.
The RECIPIENT must inform the DEPOSITOR the research project using the BIOLOGICAL RESOURCE.
Additional information
1 Mouse of the Month May 2007
Depositor Hamada, Hiroshi (RIKEN Center for Developmental Biology) Hamada, Hiroshi
Strain Status /
Availability
(Expected delivery)


Frozen
Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months