|Former Common name||p53KO, PFZ, PFZ632, B6-p53 KO|
|H-2 Haplotype||No Data|
|ES cell line||CCE/EK.CCE [129S/SvEv-Gpi1
|Genotype||a/a B/B C/C|
|Strain development||Developed by Motoya Katsuki, National Institutes of Natural Sciences (Medical Institute of Bioregulation, Kyushu University).|
|Strain description||p53 (Trp53) gene knockout mice (lacZ reporter).|
|Colony maintenance||Heterozygote x Wild-type [C57BL/6JJcl]|
|Symbol name||transformation-related protein 53|
|Symbol description||No Data|
|Symbol name||beta-galactosidase (E. coli)|
|Common name||No Data|
|Symbol description||E. coli beta galactosidase|
|References||Biochem Biophys Res Commun. 1994 Jul 29;202(2):830-7.
Gene replacement of the p53 gene with the lacZ gene in mouse embryonic stem cells and mice by using two steps of homologous recombination.
|Research applications||Cancer Research,
Cell Biology Research,
Fluorescent Proteins/lacZ System,
Immunology and Inflammation Research,
Mouse Models for Human Disease
|Specific Term and Conditions||The following terms and conditions will be requested by the DEPOSITOR.
In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested.
Biochem. Biophys. Res. Commun., 202, 830-837 (1994).
In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to Dr. Motoya Katsuki is requested. The RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE.
|2||Genotyping protocol <PCR>|
|Depositor||Sasaoka, Toshikuni (Niigata university)|
|Strain Status /