RBRC02285, C57BL/6-St3gal4<tm1.1Bsi>

RBRC No. RBRC02285
Type Targeted Mutation and TransgeneCartagena wks
Species Mus musculus
Strain name C57BL/6-St3gal4<tm1.1Bsi>
Former Common name ST34(#9 CAGCre)C57BL/6J:913 line, 913, C57BL/6-St3gal4 Tg(CAG-cre)913Bsi
H-2 Haplotype No Data
Background strain C57BL/6JJcl
Appearance
1 Appearance black
Genotype a/a B/B C/C
Strain development Developed by Dr. Yoshio Hirabayashi, RIKEN BSI in 2004. St3gal4 null allele (St3gal4<tm1.1Bsi>) was generated by transient cre expression MS12 ES cells from St3gal4<tm1Bsi> that having a loxP flanked site in this allele.
Strain description St3gal4 (ST3GAL IV) knockout mouse. St3gal4 is one of alpha 2,3-sialyltransferases that is abundantly expressed in adult placenta, ovary, and testis.
Colony maintenance Backcross to C57BL/6 (Heterozygote x C57BL/6JJcl))
Health Report
Gene Details
Promoter No Data
1 Symbol St3gal4
Symbol name ST3 beta-galactoside alpha-2,3-sialyltransferase 4
Chromosome 9
Common name Siat4c, ST3Gal IV
Symbol description No Data
2 Symbol loxP
Symbol name phage P1 loxP
Chromosome 9
Common name No Data
Symbol description No Data
References No Data

Research applications Metabolism Research,
Mouse Models for Human Disease
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
The RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR.
1. The RECIPIENT agrees to use BIOLOGICAL RESOURCE only for academic research which is expected to be publicized in scientific papers.
2. The RECIPIENT will obtain a prior written consent on the use of BIOLOGICAL RESOURCE from the DEPOSIOR/DEVELOPER. At the same time, the RECIPENT will give the DEPOSITOR/DEVELOPER the details of the research project using BIOLOGICAL RESOURCE for the DEPOSITOR/DEVELOPER to determine whether research collaboration is appropriate.
3. If the DEPOSITOR/DEVELOPER determines that the informed research project requires collaboration, a separate agreement will be formulated by both parties to establish rules such as handling of the research results.
4. If the DEPOSITOR/DEVELOPER determines that the informed research project does not requie collaboration, the RECIPIENT agrees to cite the literatire(s) designated by the DEPOSITOR/DEVEVLOPER when publicizing the research results obtained from use of BIOLOGICAL RESOURCE, and to discuss with the DEPOSITOR/DEVELOPER when application for any patents is considered.
5. If the RECIPIENT wants to crossbreed BIOLOGICAL RESOURCE with other genetically engineered mice, the RECIPIENT will obtain a prior written consent from the DEPOSITOR/DEVELOPER.
6. The RECIPIENT will not distribute the BIOLOGICAL RESOURCE to any other individual or entity.
Additional information
1 Lab HP
2 Genotyping protocol <PCR>
Depositor Hirabayashi, Yoshio (RIKEN Center for Brain Science) Hirabayashi, Yoshio
Strain Status /
Availability
(Expected delivery)


Frozen
Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months