RBRC02316, B6.Cg-Ndn<tm1Ky>

RBRC No. RBRC02316
Type Targeted Mutation CongenicCartagena
Species Mus musculus
Strain name B6.Cg-Ndn<tm1Ky>
Former Common name Necdin KO, C57BL/6
H-2 Haplotype No Data
ES cell line TT2 [(C57BL/6NCrlj x CBA/JNCrlj)F1]
Background strain No Data
Appearance
1 Appearance No Data
Genotype No Data
Strain description No Data
Health Report No Data
Gene Details
Promoter No Data
1 Symbol Ndn
Symbol name Necdin
Chromosome 7
Common name Peg6
Symbol description No Data
2 Symbol poly A
Symbol name poly A
Chromosome 7
Common name No Data
Symbol description No Data
Promoter mouse phosphoglycerate kinase promoter (PGK promoter)
3 Symbol neo
Symbol name neomycin resistance gene (E. coli)
Chromosome 7
Common name neo; neomycin;
Symbol description No Data
References J Neurosci. 2005 Jul 27;25(30):7090-9.
J Neurosci. 2006 May 17;26(20):5383-92.
J Neurosci. 2006 Nov 15;26(46):12003-13.

Disruption of the paternal necdin gene diminishes TrkA signaling for sensory neuron survival.
Disruption of the paternal necdin gene diminishes TrkA signaling for sensory neuron survival.
Disruption of the paternal necdin gene diminishes TrkA signaling for sensory neuron survival.
Research applications Developmental Biology Research,
Mouse Models for Human Disease,
Neurobiology Research
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
The RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR.
The RECIPIENT needs to contact the DEPOSITOR for a reciprocal exchange of information on the use of the RESOURCE. The RECIPIENT may be requested to collaborate with the DEPOSITOR depending on the research contents.
Additional information
1 Lab HP
2 Genotyping protocol <PCR>
Depositor Yoshikawa, Kazuaki (Osaka University) Yoshikawa, Kazuaki
Strain Status /
Availability
(Expected delivery)


Frozen
Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months