RBRC02337, B6.129P2-Top2a<tm1Skmz>

RBRC No. RBRC02337
Type Targeted MutationCartagena wks
Species Mus musculus
Strain name B6.129P2-Top2a<tm1Skmz>
Former Common name Topoisomerase II aloha knockout mouse
H-2 Haplotype No Data
Background strain C57BL/6
Appearance
1 Appearance No Data
Genotype No Data
Strain description No Data
Health Report
Gene Details
Promoter No Data
1 Symbol Top2a
Symbol name topoisomerase (DNA) II alpha
Chromosome 11
Common name DNA Topoisomerase II alpha, Top-2
Symbol description No Data
2 Symbol neo
Symbol name neomycin resistance gene (E. coli)
Chromosome 11
Common name neo; neomycin;
Symbol description No Data
References Genes Cells. 2003 Apr;8(4):393-402.

Enforced cytokinesis without complete nuclear division in embryonic cells depleting the activity of DNA topoisomerase IIalpha.
Enforced cytokinesis without complete nuclear division in embryonic cells depleting the activity of DNA topoisomerase IIalpha.
Research applications Cancer Research
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
The RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR.
In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested.
Genes Cells, 8, 393-402 (2003). Cancer Lett., 166, 71-77 (2001)
The RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR.
Additional information
1 Lab HP (Japanese)
2 Genotyping protocol <PCR>
Depositor Sekimizu, Kazuhisa (The University of Tokyo) Sekimizu, Kazuhisa
Strain Status /
Availability
(Expected delivery)


Frozen
Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months

Sperm
Cryopreserved sperm : Within 1 month
Recovered litters from cryopreserved sperm : 2-4 months