RBRC02385, B6.129-Rps6kb1<tm1Nte>

RBRC No. RBRC02385
Type Targeted MutationCartagena
Species Mus musculus
Strain name B6.129-Rps6kb1<tm1Nte>
Former Common name p70s6 Knockout mice
H-2 Haplotype No Data
ES cell line R1 [(129X1/SvJ x 129S1/Sv)F1-Kitl<+>]
Background strain C57BL/6NCrlCrlj
1 Appearance No Data
Genotype No Data
Strain description No Data
Health Report
Gene Details
Promoter No Data
1 Symbol Rps6kb1
Symbol name ribosomal protein S6 kinase, polypeptide 1
Chromosome 11
Common name 2610318I15Rik, p70/85s6k, p70s6k, S6K1
Symbol description No Data
Promoter herpes simplex virus thymidine kinase promoter (HSV tk promoter)
2 Symbol neo
Symbol name neomycin resistance gene (E. coli)
Chromosome 11
Common name neo; neomycin;
Symbol description No Data

Research applications Cell Biology Research
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
The RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR.
In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested.
Use of the BIOLOGICAL RESOURCE or descendants by for-profit entities for Commercial Purposes requires a use license from DEPOSITOR. RIKEN BRC agrees to inquire whether the party requesting the BIOLOGICAL RESOURCE is a for-profit entity or is using the BIOLOGICAL RESOURCE of descendants for Commercial Purposes, and if so, will advise the party that it must first obtain a use license from DEPOSITOR before receiving the BIOLOGICAL RESOURCE.
Commercial Purposes shall include, but not be limited to, uses of the BIOLOGICAL RESOURCE of descendants by any organization, including recipient, to perform contract research, to screen compound libraries, to produce or manufacture products for general sale, or to conduct research activities that result in any sale, lease, license, or transfer of industrially sponsored academic research shall not be considered a use of the BIOLOGICAL RESOURCE for Commercial Purposes per se, unless any of the above conditions of this definition are met.
Additional information
1 No Data
2 Genotyping protocol <PCR>
Depositor Gelfand, Erwin W. (National Jewish Medical and Research Center) Gelfand, Erwin W.
Strain Status /
(Expected delivery)

Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months

Cryopreserved sperm : Within 1 month
Recovered litters from cryopreserved sperm : 2-4 months
BRC mice in Publications
Title Journal
A disputed evidence on obesity: comparison of the effects of Rcan2(-/-) and Rps6kb1(-/-) mutations on growth and body weight in C57BL/6J mice. J Zhejiang Univ Sci B. 17: 657 (2016).(27604858)
Zhao J, Li SW, Gong QQ, Ding LC, Jin YC, Zhang J, Gao JG, Sun XY.