RBRC02392, B6.129P2-Jdp2<tm2Kkyo>/Rbrc

RBRC No. RBRC02392
Type Targeted MutationCartagena
Species Mus musculus
Strain name B6.129P2-Jdp2<tm2Kkyo>/Rbrc
Former Common name B6.129P2-Jundm2
H-2 Haplotype No Data
ES cell line E14 [129P2/OlaHsd]
Background strain C57BL/6
Appearance
1 Appearance black
Genotype a/a B/B C/C
Strain development Developed by Drs. Yokoyama KK and Pan J, RIKEN BioResource Center. The E14 ES cells originated from 129P2/OlaHsd were used. The knock-out mice are under backcrossing to C57BL/6J strain.
Strain description JDP2 coding region was disrupted.
Colony maintenance Heterozygote x Wild-type [C57BL/6J]
Health Report
Gene Details
Promoter No Data
1 Symbol Jdp2
Symbol name Jun dimerization protein 2
Chromosome 12
Common name Jdp2, TIF
Symbol description No Data
2 Symbol Frt
Symbol name yeast FRT (flippase recombination target) site
Chromosome 12
Common name No Data
Symbol description No Data
3 Symbol Frt
Symbol name yeast FRT (flippase recombination target) site
Chromosome 12
Common name No Data
Symbol description No Data
4 Symbol loxP
Symbol name phage P1 loxP
Chromosome 12
Common name No Data
Symbol description No Data
5 Symbol loxP
Symbol name phage P1 loxP
Chromosome 12
Common name No Data
Symbol description No Data
Promoter mouse phosphoglycerate kinase promoter (PGK promoter)
6 Symbol neo
Symbol name neomycin resistance gene (E. coli)
Chromosome 12
Common name No Data
Symbol description No Data
References No Data

Research applications Cre/loxP system,
FLP/frt system
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
The RECIPIENT of BIOLOGICAL RESOURCE must obtain a prior written consent on use of it from the DEVELOPER Dr. Kazushige YOKOYAMA (kazu@kmu.edu.tw).
Additional information
1 No Data
2 Genotyping protocol <PCR>
Depositor Obata, Yuichi (RIKEN, BioResource Center) Obata, Yuichi
Strain Status /
Availability
(Expected delivery)


Frozen
Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months

Sperm
Cryopreserved sperm : Within 1 month
Recovered litters from cryopreserved sperm : 2-4 months
BRC mice in Publications
Title Journal
(PMID)
Author
The transcription factor T-box3 regulates Colony Stimulating Factor 1-dependent Jun Dimerization Protein 2 expression and plays an important role in osteoclastogenesis. J Biol Chem. (2014).(24394418)
Yao C, Yao GQ, Sun BH, Zhang C, Tommasini SM, Insogna K.