Strain Data Sheet

RBRC02422

Strain Information

Image
BRC No.RBRC02422
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameB6.129S2-Mdk<tm1Tmu>
Former Common nameMdk-KO/C57BL/6J
H-2 Haplotype
ES Cell line
Background strain
Appearance
Strain development
Strain description
Colony maintenance
ReferencesJ. Clin. Invest., 105, 489-495 (2000) 10683378
Arthritis Rheum., 50, 1420-1429 (2004). 15146411
Am. J. Pathol., 168, 9-19 (2006) 16400005
Circulation, 114, 1713-1720 (2006) 17015789
Am. J. Pathol., 165, 1603-1612 (2004) 15509530
J. Cell Sci., 117, 5405-5415 (2004) 15466886
J. Biochem., 132, 359-371 (2002). 12204104
Genes Cells, 3, 811-822 (1998). 10096002

Health Report

Examination Date / Room / Rack

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Mdkmidkine2Mdk<tm1Tmu>targeted mutation 1, Takashi MuramatsuMek, MK

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
neoneomycin resistance gene (E. coli)2neo; neomycin;herpes simplex virus thymidine kinase promoter (HSV tk promoter)

Ordering Information

Donor DNApolyoma virus thymidine kinase gene promoter, E. coli neomycin resistance gene, mouse Mdk genomic DNA
Research applicationCancer Research
Cell Biology Research
Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Genes Cells, 3, 811-822 (1998). In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR (Dr. Hisako Muramatsu) is requested.
DepositorHisako Muramatsu (Nagoya University)
Strain Statusan icon for Frozen embryosFrozen embryos
an icon for Frozen spermFrozen sperm
Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
Cryopreserved sperm (within 1 month)
Cryopreserved embryos (within 1 month)
Additional Info.Necessary documents for ordering:
  1. Order form (Japanese / English)
  2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
  3. Acceptance of responsibility for living modified organism (Japanese / English)

Genotyping protocol -PCR-

BRC mice in Publications

Chen H, He D, Lasek AW.
Midkine in the mouse ventral tegmental area limits ethanol intake and Ccl2 gene expression.
Genes Brain Behav 16(7) 699-708(2017) 28398003