RBRC02460, B6.Cg-Hras1<tm1Mok> Tg(cre) Tg(lacZ)

RBRC No. RBRC02460
Type Targeted Mutation and TransgeneCartagena
Species Mus musculus
Strain name B6.Cg-Hras1<tm1Mok> Tg(cre) Tg(lacZ)
Former Common name H-ras-KO, Cre, LacZTg, B6-Hras KO/Cre lacZ Tg
H-2 Haplotype No Data
ES cell line CCE/EK.CCE [129S/SvEv-Gpi1]
Background strain No Data
1 Appearance No Data
Genotype No Data
Strain development Developed by Motoya Katsuki, National Institutes of Natural Sciences.
Strain description Triple mutant mice having a Kras gene knockout, cre and lacZ transgene.
Health Report No Data
Gene Details
Promoter No Data
1 Symbol Hras
Symbol name Harvey rat sarcoma virus oncogene
Chromosome 7
Common name c-H-ras, c-rasHa, H-ras, Ha-ras, Harvey-ras, Hras-1, ras
Symbol description No Data
2 Symbol neo
Symbol name neomycin resistance gene (E. coli)
Chromosome 7
Common name neo; neomycin;
Symbol description No Data
3 Symbol cre
Symbol name Phage P1 Cre recombinase
Chromosome No Data
Common name No Data
Symbol description No Data
4 Symbol lacZ
Symbol name beta-galactosidase (E. coli)
Chromosome No Data
Common name No Data
Symbol description E. coli beta galactosidase
References Oncogene. 2000 Jun 15;19(26):2951-6.

Targeted deletion of the H-ras gene decreases tumor formation in mouse skin carcinogenesis.
Research applications No Data
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested.
Oncogene, 19, 2951-2956 (2000).
In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to Dr. Motoya Katsuki is requested. The RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE.
Additional information
1 No Data
Depositor Sasaoka, Toshikuni (Niigata university) Sasaoka, Toshikuni
Strain Status /
(Expected delivery)

Preparing for distribution
Preparing for distribution
(Please note that it may take more than 6 months to make arrangements to distribute.)

Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months