Strain Data Sheet
RBRC02477
Strain Information | |
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| Image | |
| BRC No. | RBRC02477 |
| Type | Targeted Mutation |
| Species | Mus musculus |
| Strain name | B6;129-Grin2a<tm1Nak> Grin2b<tm1Stl> Drd2<tm1Mok> Drd3<tm1Mok> Drd4<tm1Mok> |
| Former Common name | B6-NR2A/NR2B/D2R/D3R/D4R KO |
| H-2 Haplotype | |
| ES Cell line | |
| Background strain | |
| Appearance | |
| Strain development | Developed by Motoya Katsuki, National Institutes of Natural Sciences. |
| Strain description | NR2A (Grin2a), NR2B (Grin2b), D2R (Drd2), D3R (Drd3) and D4R (Drd4) genes multiple knockout mice. |
| Colony maintenance | |
| References | J. Neurosci., 16, 7859-7867 (1996). 8987814 Genes Cells. 1(2):253-68 (1996). 9140068 |
Health Report | |
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| Examination Date / Room / Rack | |
Gene | |
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| Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Grin2aglutamate receptor, ionotropic, NMDA2A (epsilon 1)16Grin2a<tm1Nak>targeted mutation 1, Shigetada Nakanishi Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter EcogptE.coli xanthine phosphoribosyltransferase16Ecogptmouse phosphoglycerate kinase promoter (PGK promoter) Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter neoneomycin resistance gene (E. coli)16neo; neomycin;herpes simplex virus thymidine kinase promoter (HSV tk promoter) Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter neoneomycin resistance gene (E. coli)16neo; neomycin;herpes simplex virus thymidine kinase promoter (HSV tk promoter) Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Grin2bglutamate receptor, ionotropic, NMDA2B (epsilon 2)6Grin2b<tm1Stl>targeted mutation 1, Susumu TonegawaGluRepsilon2, NMDAR2B, Nmdar2b, NR2B Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter neoneomycin resistance gene (E. coli)6neo; neomycin; Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter EcogptE.coli xanthine phosphoribosyltransferase7Ecogptmouse phosphoglycerate kinase promoter (PGK promoter) Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter neoneomycin resistance gene (E. coli)7neo; neomycin;mouse RNA polymerase II large subunit promoter Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter neoneomycin resistance gene (E. coli)9neo; neomycin;herpes simplex virus thymidine kinase promoter (HSV tk promoter) |
Ordering Information | |
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| Donor DNA | herpes simplex virus thymidine kinase promoter (HSV tk promoter), E coli neo, mouse phosphoglycerate kinase promoter (PGK promoter), E. coli xanthine phosphoribosyltransferase(Ecogpt), mouse RNA polymerase II large subunit promoter, mouse NMDAR2A genomic DNA, mouse NMDA2B genomic DNA, mouse Drd2 genomic DNA, mouse Drd3 genomic DNA, mouse Drd4 genomic DNA |
| Research application | Neurobiology Research |
| Specific Term and Conditions | In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. J. Nerurosci., 16, 7859-7867 (1996).In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to Drs. Motoya Katsuki and Toshikuni Sasaoka is requested. The RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE. |
| Depositor | Toshikuni Sasaoka (Niigata University) |
| Strain Status |  Frozen embryos |
| Strain Availability |  Recovery and QC required prior to distribution |
| Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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| No Data |