| RBRC No. | RBRC02583 |
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|---|---|---|---|---|---|---|---|---|---|
| Type | Targeted Mutation |
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| Species | Mus musculus | ||||||||
| Strain name | B6.Cg-Drd1a<tm1Mok> Drd2<tm1Mok> Tg(EGFP) | ||||||||
| Former Common name | D1EGFP,D1R,D2R, D1RD2R KO/GFP Tg | ||||||||
| H-2 Haplotype | No Data | ||||||||
| Background strain | No Data | ||||||||
| Appearance | |||||||||
| 1 | Appearance | No Data | |||||||
| Genotype | No Data | ||||||||
| Strain development | Developed by Motoya Katsuki, National Institutes of Natural Sciences. | ||||||||
| Strain description | D1R (Drd1a) gene, D2R (Drd2) gene and GFP Tg triple mutant mice. | ||||||||
| Health Report | No Data | ||||||||
| Gene Details | |||||||||
| Promoter | No Data | ||||||||
| 1 | Symbol | Drd1 | |||||||
| Symbol name | dopamine receptor D1 | ||||||||
| Chromosome | 13 | ||||||||
| Common name | C030036C15Rik, D1 receptor, Drd-1, Drd1, Gpcr15 | ||||||||
| Symbol description | No Data | ||||||||
| 2 | Symbol | Ecogpt | |||||||
| Symbol name | E.coli xanthine phosphoribosyltransferase | ||||||||
| Chromosome | 13 | ||||||||
| Common name | No Data | ||||||||
| Symbol description | No Data | ||||||||
| 3 | Symbol | Drd2 | |||||||
| Symbol name | dopamine receptor D2 | ||||||||
| Chromosome | 9 | ||||||||
| Common name | D2 receptor, D2R, Drd-2 | ||||||||
| Symbol description | No Data | ||||||||
| Promoter | herpes simplex virus thymidine kinase promoter (HSV tk promoter) | ||||||||
| 4 | Symbol | neo | |||||||
| Symbol name | neomycin resistance gene (E. coli) | ||||||||
| Chromosome | 13 | ||||||||
| Common name | neo; neomycin; | ||||||||
| Symbol description | No Data | ||||||||
| 5 | Symbol | neo | |||||||
| Symbol name | neomycin resistance gene (E. coli) | ||||||||
| Chromosome | 9 | ||||||||
| Common name | neo; neomycin; | ||||||||
| Symbol description | No Data | ||||||||
| References | Genes Cells. 1996 Feb;1(2):253-68. Dopamine D2 receptor plays a critical role in cell proliferation and proopiomelanocortin expression in the pituitary.
Dopamine D2 receptor plays a critical role in cell proliferation and proopiomelanocortin expression in the pituitary. |
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| Research applications | No Data | ||||||||
| Specific Term and Conditions | The following terms and conditions will be requested by the DEPOSITOR. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. J. Neurosci., 28, 13390-13400 (2008). Genes Cells, 1, 253-268 (1996). In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to Dr. Motoya Katsuki is requested. The RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE. |
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| Additional information | |||||||||
| 1 | No Data | ||||||||
| Depositor | Sasaoka, Toshikuni (Niigata university)  |
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| Strain Status / Availability (Expected delivery) |
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