RBRC02598, B6;129-Mutyh<tm1Yun>

RBRC No. RBRC02598
Type Targeted MutationCartagena
Species Mus musculus
Strain name B6;129-Mutyh<tm1Yun>
Former Common name MYH KO
H-2 Haplotype No Data
ES cell line CCE28 [129/Sv]
Background strain No Data
Appearance
1 Appearance No Data
Genotype No Data
Strain development Developed by Yusaku Nakabeppu, Medical Institute of Bioregulation, Kyushu University. CCE28 ES cells derived from 129/Sv were used to generate the knockout mice. The mice were crossed to C57BL/6.
Strain description MYH (Mutyh) gene knockout mice. Exons 8 to 15 were replaced with a pol II neo cassette. Homozygous mutant mice show decreased susceptibility to neuronal excitotoxicity.
Colony maintenance Heterozygote x Wild-type [C57BL/6JJcl]
Health Report No Data
Gene Details
Promoter No Data
1 Symbol Mutyh
Symbol name mutY homolog (E. coli)
Chromosome 4
Common name No Data
Symbol description No Data
2 Symbol neo
Symbol name neomycin resistance gene (E. coli)
Chromosome 4
Common name No Data
Symbol description No Data
References

Research applications Neurobiology Research
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested.
J. Biol. Chem., 278, 38121-38124 (2003).
In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to Dr. Motoya Katsuki is requested. The RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE.
Additional information
1 No Data
Depositor Sasaoka, Toshikuni (Niigata university) Sasaoka, Toshikuni
Strain Status /
Availability
(Expected delivery)


Preparing for distribution
Preparing for distribution
(Please note that it may take more than 6 months to make arrangements to distribute.)

Frozen
Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months