RBRC02684, B6J.C-Atp2b2<wri>/Oda

RBRC No. RBRC02684
Type Spontaneous Mutation
Species Mus musculus
Strain name B6J.C-Atp2b2<wri>/Oda
Former Common name No Data
H-2 Haplotype No Data
Background strain C57BL/6
Appearance
1 Appearance black
Genotype a/a B/B C/C
Strain development Spontaneous mutant arose in BALB/c inbred mice, found by Mr. Michio Ohmura, Ohmura Institute for Laboratory Animals in 1984. The Wriggle mice were maintained by Dr. Nobutaka Ohsawa, Kitasato University School of Medicine, and then backcrossed to C57BL/6J by Dr. Sen-ichi Oda, Nagoya University in 2005.
Strain description Wriggle Mouse Sagami (wri), a point mutation was occurred in a Atp2b2 gene that is an isoform of Calmodulin-dependent plasma membrane Ca<2+>-ATPase. Homozygous mutant mice show severe dystonic movements of the trunk and extremities.
Colony maintenance Heterozygote x Wild-type [C57BL/6JJmsSlc]
Homozygous mutant mice are viable, but infertile due to a failure of mating behavior.
Health Report No Data
Gene Details
Promoter No Data
1 Symbol Atp2b2
Symbol name ATPase, Ca++ transporting, plasma membrane 2
Chromosome 6
Common name No Data
Symbol description No Data
References

Research applications Neurobiology Research,
Sensorineural Research
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
The RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR.
The RECIPIENT of BIOLOGICAL RESOURCE must obtain a prior written consent on use of it from the DEPOSITOR/DEVELOPER.
Additional information
1 No Data
2 Genotyping protocol <PCR>
Depositor Oda, Senichi (Nagoya University) Oda, Senichi
Strain Status /
Availability
(Expected delivery)


Frozen
Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months

Sperm
Cryopreserved sperm : Within 1 month
Recovered litters from cryopreserved sperm : 2-4 months