RBRC02846, 129S6/SvEvTac-Crx<tm1Clc>

RBRC No. RBRC02846
Type Targeted MutationCartagena
Species Mus musculus
Strain name 129S6/SvEvTac-Crx<tm1Clc>
Former Common name CRX K.O.
H-2 Haplotype No Data
Background strain 129S6/SvEvTac
1 Appearance light-bellied agouti
Genotype A/A B/B C/C
Strain development Developed by Dr. Takahisa Furukawa, Harvard Medical School in 1999.
Strain description Crx gene knockout mice. Homozygous mutant mice lack a outer segment of retinal photoreceptor.
Colony maintenance Sibling x Sibling (Homozygote x Homozygote)
Homozygous mutant mice are viable and fertile
Health Report
Gene Details
Promoter No Data
1 Symbol Crx
Symbol name cone-rod homeobox containig gene
Chromosome 7
Common name cone-rod homeobox containg gene
Symbol description No Data
Promoter mouse phosphoglycerate kinase promoter (PGK promoter)
2 Symbol neo
Symbol name neomycin resistance gene (E. coli)
Chromosome No Data
Common name neo; neomycin;
Symbol description No Data

Research applications No Data
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested.
Nat. Genet., 23, 466-470 (1999).
Additional information
1 No Data
2 Genotyping protocol <PCR>
Depositor Furukawa, Takahisa (Osaka Bioscience Institute) Furukawa, Takahisa
Strain Status /
(Expected delivery)

Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months

Live mouse :
BRC mice in Publications
Title Journal
Behavioral analyses of visually impaired Crx knockout mice revealed sensory compensation in exploratory activities on elevated platforms. Behav Brain Res. (2013).(24140563)
Iura Y, Udo H.