RBRC02847, 129S6/SvEvTac-Dkk3<tm1Tfur>

RBRC No. RBRC02847
Type Targeted MutationCartagena
Species Mus musculus
Strain name 129S6/SvEvTac-Dkk3<tm1Tfur>
Former Common name DKK3 K.O.
H-2 Haplotype No Data
ES cell line TC1 [129S6/SvEvTac]
Background strain 129S6/SvEvTac
Appearance
1 Appearance light-bellied agouti
Genotype A/A B/B C/C
Strain development Developed by Dr. Takahisa Furukawa, Osaka Bioscience Institute in 2007.
Strain description Dkk3 knockout mice. Homozygous mutant mice show no obvious phenotype.
Colony maintenance Sibling Mating (Homozygote x Homozygote)
Health Report
Gene Details
Promoter No Data
1 Symbol DKK3
Symbol name dickkopf homolog 3 (Xenopus laevis)
Chromosome 7
Common name dickkopf homolog 3 (Xenopus laevis)
Symbol description No Data
2 Symbol No Data
Symbol name SV40 PolyA signal
Chromosome 7
Common name No Data
Symbol description No Data
Promoter mouse phosphoglycerate kinase promoter (PGK promoter)
3 Symbol neo
Symbol name neomycin resistance gene (E. coli)
Chromosome 7
Common name neo; neomycin;
Symbol description No Data
References No Data

Research applications No Data
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested.
Additional information
1 No Data
2 Genotyping protocol <PCR>
Depositor Furukawa, Takahisa (Osaka Bioscience Institute) Furukawa, Takahisa
Strain Status /
Availability
(Expected delivery)


Frozen
Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months

Sperm
Cryopreserved sperm : Within 1 month
Recovered litters from cryopreserved sperm : 2-4 months
BRC mice in Publications
Title Journal
(PMID)
Author
Phosphatase WIP1 regulates adult neurogenesis and WNT signaling during aging. J. Clin. Invest.124(7): 3263-73. (2014).(24911145)
Zhu Y, Demidov ON, Goh AM, Virshup DM, Lane DP, Bulavin DV.
Expression analysis of Dickkopf-related protein 3 (Dkk3) suggests its pleiotropic roles for a secretory glycoprotein in adult mouse. J. Mol. Histol. (2016).(27866302)
Inoue J, Fujita H, Bando T, Kondo Y, Kumon H, Ohuchi H.