RBRC02976, B6.129P2-Ahrr<tm1Yfk>

RBRC No. RBRC02976
Type Targeted MutationCartagena
Species Mus musculus
Strain name B6.129P2-Ahrr<tm1Yfk>
Former Common name No Data
H-2 Haplotype No Data
Background strain No Data
Appearance
1 Appearance black
Genotype a/a B/B C/C
Strain development Developed by Dr. Yoshiaki Fujii-Kuriyama, University of Tsukuba.
Strain description AhR repressor (arly-hydrocarbon receptor repressor) gene knock-out mice. AhR repressor is an AhR-related bHLH-PAS transcription factor.
Colony maintenance Heterozygote x Wild-type [C57BL/6JJcl]
Homozygous mutant mice are viable and fertile.
Health Report
Gene Details
Promoter No Data
1 Symbol Ahrr
Symbol name aryl-hydrocarbon receptor repressor
Chromosome 13
Common name No Data
Symbol description No Data
2 Symbol lacZ
Symbol name beta-galactosidase (E. coli)
Chromosome No Data
Common name No Data
Symbol description E. coli beta galactosidase
Promoter Herpes simplex virus thymidine kinase promoter (HSV tk promoter)
3 Symbol neo
Symbol name neomycin resistance gene (E. coli)
Chromosome No Data
Common name neo; neomycin;
Symbol description No Data
References Biochem Biophys Res Commun. 2008 Jan 18;365(3):562-7. Epub 2007 Nov 20.

Inducibility of cytochrome P450 1A1 and chemical carcinogenesis by benzo[a]pyrene in AhR repressor-deficient mice.
Research applications No Data
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested.
Biochem. Biophys. Res. Commun., 365, 562-567 (2008).
In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested.
The RECIPIENT agrees to include the DEPOSITOR as a co-author in any publications resulted by the use of the BIOLOGICAL RESOURCE during first TWO years after deposition by the DEPOSITOR to the RIKEN BRC. The RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE.
Additional information
1 No Data
2 Genotyping protocol <PCR>
Depositor Fujii, Yoshiaki (University of tsukuba) Fujii, Yoshiaki
Strain Status /
Availability
(Expected delivery)


Frozen
Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months

Sperm
Cryopreserved sperm : Within 1 month
Recovered litters from cryopreserved sperm : 2-4 months