RBRC03661, B6;129-Arx<tm(P355L)Kki>/1Rbrc

RBRC No. RBRC03661
Type Targeted MutationCartagena
Species Mus musculus
Strain name B6;129-Arx<tm(P355L)Kki>/1Rbrc
Former Common name Arx P355L-1 KI (B6)
H-2 Haplotype No Data
ES cell line CCE/EK.CCE [129S/SvEv-Gpi1]
Background strain No Data
1 Appearance No Data
Genotype No Data
Strain development Developed by Dr. Kunio Kitamura, Mistubishi Kagaku Insitute of Life Sciences.
Strain description Arx P355L variant knock-in mice
Colony maintenance Heterozygote x Wild-type [C57BL/6J]
Health Report
Gene Details
Promoter No Data
1 Symbol Arx
Symbol name aristaless related homeobox
Chromosome X
Common name No Data
Symbol description No Data

Research applications No Data
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
The BIOLOGICAL RESOURCE shall be used only for academic research purposes by
a non-profit organization.
The RECIPIENT of a non-profit organization must prior contact RIKEN BRC and
negotiate with Mitsubishi Chemical Corporation to use the BIOLOGICAL
RESOURCE for purposes of other than academic research.
In publishing the research results to be obtained by use of the BIOLOGICAL
RESOURCE in relevant journals and meetings, the RECIPIENT must stipulate the
source of the BIOLOGICAL RESOURCE and an acknowledgment to Mitsubishi
Chemical Corporation.
The RECIPIENT agrees that RIKEN BRC informs annually to Mitsubishi Chemical
Corporation of RECIPIENT organization, RECIPIENT name, the specific research
purpose and the date of distribution.
Additional information
1 No Data
2 Genotyping protocol <PCR>
Depositor Kitamura, Kunio (Mitsubishi Chemical Corporation) Kitamura, Kunio
Strain Status /
(Expected delivery)

Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months
BRC mice in Publications
Title Journal
Aristaless-Related Homeobox Plays a Key Role in Hyperplasia of the Pancreas Islet alpha-Like Cells in Mice Deficient in Proglucagon-Derived Peptides. PLoS One.8(5): e64415 (2013).(23671715)
Xu S, Hayashi Y, Takagishi Y, Itoh M, Murata Y.