RBRC04199, B6.129P2-Cxcl12<tm1Tng>

RBRC No. RBRC04199
Type Targeted MutationCartagena
Species Mus musculus
Strain name B6.129P2-Cxcl12<tm1Tng>
Former Common name CXCL12 KO
H-2 Haplotype No Data
ES cell line E14.1 [129P2/OlaHsd]
Background strain No Data
Appearance
1 Appearance No Data
Genotype No Data
Strain description No Data
Health Report
Gene Details
Promoter No Data
1 Symbol Cxcl12
Symbol name chemokine (C-X-C motif) ligand 12
Chromosome 6
Common name No Data
Symbol description No Data
Promoter herpes simplex virus thymidine kinase promoter (HSV tk promoter)
2 Symbol neo
Symbol name neomycin resistance gene (E. coli)
Chromosome 6
Common name neo; neomycin;
Symbol description No Data
References

Research applications Immunology and Inflammation Research
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
Prior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT is requested to make a Material Transfer Agreement with the DEPOSITOR. For use of the BIOLOGICAL RESOURCE by a for-profit institution, the RECIPIENT must reach agreement on terms and conditions of use of it with DEPOSITOR and must obtain a prior written consent form the DEPOSITOR.
Additional information
1 No Data
2 Genotyping protocol <PCR>
Depositor Nagasawa, Takashi (Institute for frontier medical sciences, Kyoto university) Nagasawa, Takashi
Strain Status /
Availability
(Expected delivery)


Frozen
Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months

Sperm
Cryopreserved sperm : Within 1 month
Recovered litters from cryopreserved sperm : 2-4 months
BRC mice in Publications
Title Journal
(PMID)
Author
CXCL12 in early mesenchymal progenitors is required for haematopoietic stem-cell maintenance. Nature.495(7440): 227-30 (2013).(23434756)
Greenbaum A, Hsu YM, Day RB, Schuettpelz LG, Christopher MJ, Borgerding JN, Nagasawa T, Link DC.