RBRC04434, B6.129-Msi1<tm1Okn>

RBRC No. RBRC04434
Type Targeted MutationCartagena
Species Mus musculus
Strain name B6.129-Msi1<tm1Okn>
Former Common name No Data
H-2 Haplotype No Data
Background strain No Data
1 Appearance No Data
Genotype No Data
Strain description Msi1 deficient mice
C57BL/6J background Msi1 deficient mice frequently died of obstructive hydrocephalus within a couple of month with aberrant cell proliferation around cerebral aqueduct. (Sakakibara S et al. Proc Natl Acad Sci USA. 2002) Both male and female are infertile because of the early death of hydrocephalus.
On the other hand, CD-1 (ICR) background Msi1 deficient mice survive to adult without gross anatomical phenotype. Since both male and female are fertile, it is possible to mate between Msi1 null mice. (Unpublished data)
Health Report
Gene Details
Promoter No Data
1 Symbol Msi1
Symbol name Musashi homolog 1 (Drosophila)
Chromosome 5
Common name No Data
Symbol description No Data
Promoter mouse phosphoglycerate kinase promoter (PGK promoter)
2 Symbol neo
Symbol name neomycin resistance gene (E. coli)
Chromosome 5
Common name neo; neomycin;
Symbol description No Data

Research applications Cell Biology Research
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested.
Proc. Natl. Acad. Sci. USA, 99, 15194-15199 (2002).
For use of the BIOLOGICAL RESOURCE, the RECIPIENT must reach agreement on terms and conditions of use of it with DEPOSITOR and must obtain a prior written consent from the DEPOSITOR.
Additional information
1 Lab HP
Depositor Okano, Hideyuki (Keio University School of Medicine) Okano, Hideyuki
Strain Status /
(Expected delivery)

Cryopreserved sperm : Within 1 month
Recovered litters from cryopreserved sperm : 2-4 months