RBRC04741, B6.B6CB-Ltb4r2<tm1Tksh>

RBRC No. RBRC04741
Type Targeted MutationCartagena
Species Mus musculus
Strain name B6.B6CB-Ltb4r2<tm1Tksh>
Former Common name B6-BLT2 KO
H-2 Haplotype No Data
Background strain No Data
Appearance
1 Appearance No Data
Genotype No Data
Strain development Developed by Dr. Takao Shimizu, Faculty of Medicine, University of Tokyo in 2005. A lacZ-neo was inserted into the protein coding region of Ltb4r2 gene (Expression of lacZ was not detected). The mutant mice were backcrossed to C57BL/6.
Strain description No Data
Health Report
Gene Details
Promoter No Data
1 Symbol Ltb4r2
Symbol name leukotriene B4 receptor 2
Chromosome 14
Common name No Data
Symbol description No Data
References J Biol Chem. 2001 Apr 13;276(15):12454-9. Epub 2001 Jan 18.
J Exp Med. 2008 Apr 14;205(4):759-66. Epub 2008 Mar 31.

Hydroxyeicosanoids bind to and activate the low affinity leukotriene B4 receptor, BLT2.
Hydroxyeicosanoids bind to and activate the low affinity leukotriene B4 receptor, BLT2.
Hydroxyeicosanoids bind to and activate the low affinity leukotriene B4 receptor, BLT2.
Hydroxyeicosanoids bind to and activate the low affinity leukotriene B4 receptor, BLT2.
Research applications No Data
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested.
FASEB J., 24(12):4678-90 (2010).
RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE.
Additional information
1 Lab HP (Japanese)
2 Genotyping protocol <PCR>
Depositor Shimizu, Takao (The University of Tokyo, Graduate School of Medicine) Shimizu, Takao
Strain Status /
Availability
(Expected delivery)


Sperm
Cryopreserved sperm : Within 1 month
Recovered litters from cryopreserved sperm : 2-4 months