RBRC04860, B10.C-Tyr<c>/Hir

RBRC No. RBRC04860
Type Spontaneous Mutation
Species Mus musculus
Strain name B10.C-Tyr<c>/Hir
Former Common name B10-c
H-2 Haplotype No Data
Background strain No Data
Appearance
1 Appearance No Data
Genotype No Data
Strain development Developed by Tomohisa Hirobe, National Institute of Radiological Sciences in 1986. Albino (c) locus from BALB/cCrJms was backcrossed into the C57BL/10JMsHir, and then mantained by sister-brother mating.
Strain description C57BL/10 congenic strain of albino locus from BALB/c strain. Albino (a/a B/B c/c D/D P/P E/E). No melanocyte in skin and eyes.
Colony maintenance Homozygote x Homozygote
Health Report
Gene Details
Promoter No Data
1 Symbol Tyr
Symbol name tyrosinase
Chromosome 7
Common name No Data
Symbol description No Data
References



Research applications No Data
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. T. Hirobe: How are proliferation and differentiation of mouse melanocytes regulated? Pigmnet Cell Melanoma Res., 24(3):462-478 (2011). In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested.
Additional information
1 No Data
Depositor Hirobe, Tomohisa (National Institute of Radiological Sciences) Hirobe, Tomohisa
Strain Status /
Availability
(Expected delivery)


Frozen
Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months
BRC mice in Publications
Title Journal
(PMID)
Author
Melanin or melanin-like substance interacts with the N-terminal portion of prion protein and inhibits abnormal prion protein formation in prion-infected cells. J Virol. (2017).(28077650)
Hamanaka T, Nishizawa K, Sakasegawa Y, Oguma A, Teruya K, Kurahashi H, Hara H, Sakaguchi S, Doh-Ura K.