RBRC04944, B6.129S4-Il5<tm1.1Ktk>

RBRC No. RBRC04944
Type Targeted MutationCartagena
Species Mus musculus
Strain name B6.129S4-Il5<tm1.1Ktk>
Former Common name B6-IL5/Venus KI
H-2 Haplotype No Data
ES cell line AK7 [129S4/SvJaeSor]
Background strain C57BL/6JJcl
Appearance
1 Appearance No Data
Genotype No Data
Strain development Developed by Kiyoshi Takatsu, Graduate School of Medicine and Pharmaceutical, University of Toyama / Toyama Prefectural Institute for Pharmaceutical Research / The Institute of Medical Science, The University of Tokyo in 2008.
Strain description No Data
Colony maintenance Heterozygote x Wild-type [C57BL/6JJcl]
Health Report
Gene Details
Promoter No Data
1 Symbol Venus
Symbol name Green Fluorescent Protein, F46L (Jellyfish)
Chromosome 11
Common name Venus
Symbol description No Data
2 Symbol Il5
Symbol name interleukin 5
Chromosome 11
Common name No Data
Symbol description No Data
3 Symbol loxP
Symbol name phage P1 loxP
Chromosome 11
Common name No Data
Symbol description No Data
References Immunity. 1996 May;4(5):483-94.

Defective B-1 cell development and impaired immunity against Angiostrongylus cantonensis in IL-5R alpha-deficient mice.
Defective B-1 cell development and impaired immunity against Angiostrongylus cantonensis in IL-5R alpha-deficient mice.
Research applications Cre/loxP system,
Fluorescent Proteins/lacZ System
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested.
J. Immunol., 188(2):703-713 (2012).
In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested.
The RECIPIENT of BIOLOGICAL RESOURCE must obtain a prior written consent on use of it from the DEVELOPER of the Venus using Approval form (form V) (Lab Contact: Laboratory for Cell Function Dynamics, RIKEN CBS: sakurai-h@brain.riken.jp).
For use of the BIOLOGICAL RESOURCE by a for-profit institution, the RECIPIENT must reach agreement on terms and conditions of use of it with DEPOSITOR and Life tecnologies and must obtain a prior written consent from the DEPOSITOR.
RECIPIENT must contact the DEPOSITOR and Life tecnologies in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE.
Additional information
1 Approval form Form V (English)
2 Genotyping protocol <PCR>
Depositor Takatsu, Kiyoshi (UNIVERSITY OF TOYAMA) Takatsu, Kiyoshi
Strain Status /
Availability
(Expected delivery)


Frozen
Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months

Sperm
Cryopreserved sperm : Within 1 month
Recovered litters from cryopreserved sperm : 2-4 months