RBRC05065, B6.B6CB-Sox1<tm1(cre)Take>

RBRC No. RBRC05065
Type Targeted MutationCartagena
Species Mus musculus
Strain name B6.B6CB-Sox1<tm1(cre)Take>
Former Common name B6-Sox1/cre KI
H-2 Haplotype No Data
ES cell line TT2 [(C57BL/6NCrlj x CBA/JNCrlj)F1]
Background strain No Data
Appearance
1 Appearance No Data
Genotype No Data
Strain development Cre recombinase was inserted into the ATG codon start site if Sox1 by in-frame. PGK-neo cassette was removed by Flp recombinase expression.
Strain description Sox1 cre knock-in mice. knocked into the Sox1 gene. No obvious defect at the heterozygous state which is used for the conditional KO or cell tracing purposes.
Colony maintenance Heterozygote X Wild-type [C57BL/6NJcl]
Health Report
Gene Details
Promoter No Data
1 Symbol Sox1
Symbol name SRY-box containing gene 1
Chromosome 8
Common name No Data
Symbol description No Data
2 Symbol Frt
Symbol name yeast FRT (flippase recombination target) site
Chromosome 8
Common name No Data
Symbol description No Data
3 Symbol cre
Symbol name Phage P1 Cre recombinase
Chromosome 8
Common name No Data
Symbol description No Data
References Cell. 2007 Jun 29;129(7):1377-88.

Neuroepithelial cells supply an initial transient wave of MSC differentiation.
Research applications Cre/loxP system,
FLP/frt system
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
(1) In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the Accession No. CDB0525K, and Web Site (http:www.cdb.riken.jp/arg/mutant%20mice%20list.html) and the BIOLOGICAL RESOURCE is requested. (2) In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the literature designed by the DEPOSITOR is requested. (Cell, 129, 1377-1388 (2007).)
Additional information
1 No Data
2 Genotyping protocol <PCR>
Depositor RIKEN, CDB (RIKEN Center for Developmental Biology) RIKEN, CDB
Strain Status /
Availability
(Expected delivery)


Frozen
Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months

Sperm
Cryopreserved sperm : Within 1 month
Recovered litters from cryopreserved sperm : 2-4 months

Live
Live mouse :