RBRC05261, DW/J-Tpst2<grt>/Hkv

RBRC No. RBRC05261
Type Spontaneous Mutation
Species Mus musculus
Strain name DW/J-Tpst2<grt>/Hkv
Former Common name DW-grt
H-2 Haplotype No Data
Background strain No Data
Appearance
1 Appearance No Data
Genotype No Data
Strain development Developed by Takeshi Yoshida, Mie University School of Medicine. Maintained by Takashi Agui, Graduate School of Veterinary Medicine, Hokkaido University.
Strain description Hypothyroid growth-retarded mouse derived from Snell's dwarf mouse. Homozygous mutant mice show a delayed pubertal growth and hypothyroidism. Homozygous females are infertile and males show markedly-decreased fertility.
Colony maintenance Heterozygote X Wild-type
Health Report
Gene Details
Promoter No Data
1 Symbol Tpst2
Symbol name protein-tyrosine sulfotransferase 2
Chromosome 5
Common name No Data
Symbol description No Data
References J Vet Med Sci. 2008 Oct;70(10):1043-9.
Mol Endocrinol. 2007 Apr 24;.

Female infertility in grt mice is caused by thyroid hormone deficiency, not by insufficient TPST2 activity in the reproductive organs.
Female infertility in grt mice is caused by thyroid hormone deficiency, not by insufficient TPST2 activity in the reproductive organs.
Female infertility in grt mice is caused by thyroid hormone deficiency, not by insufficient TPST2 activity in the reproductive organs.
Research applications No Data
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
The RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR.
Additional information
1 No Data
2 Genotyping protocol <PCR>
Depositor Agui, Takashi (Graduate School of Veterinary Medicine, Hokkaido University) Agui, Takashi
Strain Status /
Availability
(Expected delivery)


Frozen
Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months

Sperm
Cryopreserved sperm : Within 1 month
Recovered litters from cryopreserved sperm : 2-4 months