RBRC05548, SLW

RBRC No. RBRC05548
Type Spontaneous Mutation
Species Mus musculus
Strain name SLW
Former Common name No Data
H-2 Haplotype No Data
Background strain No Data
Appearance
1 Appearance No Data
Genotype No Data
Strain development Developed by Tetsuo Kunieda, Faculty of Agriculture, Okayama University. Spontaneous mutation arose in ddY mouse colony. The mutant mouse was crossed with C57BL/6J, and maintained by sister-brother maintaining.
Strain description Short-limbed dwarfism, SLW mice. Spontaneous mutation arose in ddY mouse colony. Homozygous mice show dwarfism and most of them die before weaning. A 7-base deletion was identified in exon 8 of the Npr2 gene, resulting in a frameshift and premature termination codon appearance.
Colony maintenance Heterozygote x Wild-type
Health Report
Gene Details
Promoter No Data
1 Symbol Npr2
Symbol name natriuretic peptide receptor 2
Chromosome 4
Common name No Data
Symbol description No Data
References

Research applications No Data
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested.
Am. J. Pathol., 177, 822-888 (2010).
Prior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR.
Additional information
1 No Data
2 Genotyping protocol <PCR>
Depositor Kunieda, Tetsuo (Okayama University) Kunieda, Tetsuo
Strain Status /
Availability
(Expected delivery)


Frozen
Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months

Sperm
Cryopreserved sperm : Within 1 month
Recovered litters from cryopreserved sperm : 2-4 months