RBRC05553, B6.129P2-Pmaip1<tm1Ttg>

RBRC No. RBRC05553
Type Targeted MutationCartagena
Species Mus musculus
Strain name B6.129P2-Pmaip1<tm1Ttg>
Former Common name B6-Noxa KO
H-2 Haplotype No Data
ES cell line E14.1 [129P2/OlaHsd]
Background strain C57BL/6JJcl
1 Appearance No Data
Genotype No Data
Strain development Developed by Tsukasa Shibue and Tadatsugu Taniguchi, Graduate School of Medicine, University of Tokyo in 2003. E14.1 ES cell derived. The mutant mice were backcrossed to C57BL/6J.
Strain description Noxa (Pmaip1) gene knockout mice. A 2.4 kb genomic region including exons 1 and 2 of the Pmaip1 gene was replaced with a neomycin selection cassette. Homozygous mutant mice are resistant to X-ray irradiation-induced gastrointestinal death.
Colony maintenance Heterozygote x Wild-type [C57BL/6JJcl]
Health Report
Gene Details
Promoter No Data
1 Symbol neo
Symbol name neomycin resistance gene (E. coli)
Chromosome 18
Common name neo; neomycin;
Symbol description No Data
2 Symbol Pmaip1
Symbol name phorbol-12-myristate-13-acetate-induced protein 1
Chromosome 18
Common name No Data
Symbol description No Data

Research applications No Data
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
Prior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form.
In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested.
The RECIPIENT shall inform the DEPOSITOR about the purpose of the use of the BIOLOGICAL RESOURCE and shall limit the use within the scope of the purpose described in this Agreement. The RECIPIENT shall inform the DEPOSITOR about the results obtained by the use of the BIOLOGICAL RESOURCE.
Additional information
1 Taniguchi Lab HP
2 Genotyping protocol <PCR>
Depositor Taniguchi, Tadatsugu (The University of Tokyo, Graduate School of Medicine) Taniguchi, Tadatsugu
Strain Status /
(Expected delivery)

Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months

Cryopreserved sperm : Within 1 month
Recovered litters from cryopreserved sperm : 2-4 months