RBRC05668, B10.Cg-H2<k> Tg(H2-Ea-Cd74/MCC*T102E)29Nnak

RBRC No. RBRC05668
Type Transgene CongenicCartagena
Species Mus musculus
Strain name B10.Cg-H2<k> Tg(H2-Ea-Cd74/MCC*T102E)29Nnak
Former Common name Ii-102E, B10.BR-Ii-102E Tg#29
H-2 Haplotype No Data
Background strain No Data
Appearance
1 Appearance No Data
Genotype No Data
Strain development Developed by Naoko Nakano, Institute of Genetics and Molecular and Cellular Biology in 1996. Transgene was injected into the pronuclei of (C57BL/6 x SJL) F2 fertilized eggs. The mice were backcrossed to B10.BR over 10 times.
Strain description Ii-102E transgenic mice expressing a fusion protein of Cd74 (MHC II invariant chain) and moth cytochrome c (MCC) 88-103 peptides sequence containing a single amino acid substitution at position 102 (threonine to glutamine).
Colony maintenance Carrier x Noncarrier [or Crossing to B10.BR/SgSnSlc]
Health Report
Gene Details
Promoter No Data
1 Symbol H2
Symbol name histocompatibility-2, MHC
Chromosome 17
Common name No Data
Symbol description No Data
2 Symbol MCC
Symbol name Moth cytochrome C
Chromosome UN
Common name No Data
Symbol description No Data
3 Symbol Tg(H2-Ea-Cd74/MCC*T102E)29Nnak
Symbol name No Data
Chromosome UN
Common name No Data
Symbol description No Data
Promoter mouse MHC class II E alpha promoter
4 Symbol Cd74
Symbol name CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated)
Chromosome UN
Common name No Data
Symbol description No Data
References

Research applications Immunology and Inflammation Research
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested.
Int. Immunol., 14, 857-865 (2002).
Additional information
1 No Data
2 Genotyping protocol <PCR>
Depositor Nakano, Naoko (Tokyo university of science) Nakano, Naoko
Strain Status /
Availability
(Expected delivery)


Frozen
Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months

Sperm
Cryopreserved sperm : Within 1 month
Recovered litters from cryopreserved sperm : 2-4 months