RBRC05954, B6.129S7-Dp(7Herc2-Mkrn3)1Taku

RBRC No. RBRC05954
Type Targeted Mutation and Chromosomal AberrationCartagena
Species Mus musculus
Strain name B6.129S7-Dp(7Herc2-Mkrn3)1Taku
Former Common name B6-Dp(7C)
H-2 Haplotype No Data
ES cell line AB2.2 [129S7/SvEvBrd-Hprt]
Background strain C57BL/6JJcl
Appearance
1 Appearance No Data
Genotype No Data
Strain development Developed by Toru Takumi, Osaka Bioscience Institute and Allan Bradley, The Wellcome Trust Sanger Institute in 2004. The mutant mice were backcrossed to C57BL/6J over 20 times.
Strain description Chromosome-engineered mouse strain having a 6.3 Mb duplication of mouse chromosome 7 mirroring the human chromosome 15q11-13 duplication.
Colony maintenance Heterozygote x Wild-type [C57BL/6JJcl]
Health Report
Gene Details
Promoter No Data
1 Symbol HPRT
Symbol name hypoxanthine guanine phosphoribosyl transferase (human)
Chromosome 7
Common name No Data
Symbol description No Data
2 Symbol Herc2
Symbol name HECT and RLD domain containing E3 ubiquitin protein ligase 2
Chromosome 7
Common name No Data
Symbol description No Data
3 Symbol Mkrn3
Symbol name makorin, ring finger protein, 3
Chromosome 7
Common name No Data
Symbol description No Data
4 Symbol loxP
Symbol name phage P1 loxP
Chromosome 7
Common name No Data
Symbol description No Data
Promoter K14 promoter
5 Symbol agouti
Symbol name No Data
Chromosome 7
Common name No Data
Symbol description No Data
References

Research applications Cre/loxP system,
Developmental Biology Research,
Mouse Models for Human Disease,
Neurobiology Research
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
The RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR.
Additional information
1 Mouse of the Month Apr 2015
2 Genotyping protocol <PCR>
Depositor Takumi, Toru (RIKEN Center for Brain Science) Takumi, Toru
Strain Status /
Availability
(Expected delivery)


Frozen
Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months

Sperm
Cryopreserved sperm : Within 1 month
Recovered litters from cryopreserved sperm : 2-4 months