RBRC06142, B6.129-Tnfsf11<tm1>

RBRC No. RBRC06142
Type Targeted MutationCartagena
Species Mus musculus
Strain name B6.129-Tnfsf11<tm1>
Former Common name RANKL flox, B6-Tnfsf11 floxed
H-2 Haplotype No Data
ES cell line Not specified (ES cell)
Background strain No Data
Appearance
1 Appearance No Data
Genotype No Data
Strain development Developed by Toshio Fumoto and Kyoji Ikeda, National Center for Geriatrics and Gerontology (2009-2013). 129Sv/EvTac derived ES cells were used. Frt flanked neo cassette was removed by crossing with CAG-FLPe (B6). The mutant mice were crossed C57BL/6 OVER 9 times.
Strain description RANKL (Tnfsf11) gene floxed mice. Exons 3 and 4 were flanked by loxP site.
Colony maintenance Homozygote x Homozygote [or Crossing to C57BL/6JJmsSlc] Homozygous mice show no obvious abnormality.
Health Report No Data
Gene Details
Promoter No Data
1 Symbol Frt
Symbol name yeast FRT (flippase recombination target) site
Chromosome 14
Common name No Data
Symbol description No Data
2 Symbol Tnfsf11
Symbol name tumor necrosis factor (ligand) superfamily, member 11
Chromosome 14
Common name No Data
Symbol description No Data
3 Symbol loxP
Symbol name phage P1 loxP
Chromosome 14
Common name No Data
Symbol description No Data
References

Research applications Cre/loxP system,
FLP/frt system,
Mouse Models for Human Disease
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested.
J. Bone. Miner. Res., 29, 830-842 (2014).
Additional information
1 No Data
2 Genotyping protocol <PCR>
Depositor Ikeda, Kyoji (National Center for Geriatrics and Gerontology) Ikeda, Kyoji
Strain Status /
Availability
(Expected delivery)


Frozen
Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months

Sperm
Cryopreserved sperm : Within 1 month
Recovered litters from cryopreserved sperm : 2-4 months