RBRC06190, D2;129-Myod1<tm1Jae>

RBRC No. RBRC06190
Type Targeted MutationCartagena
Species Mus musculus
Strain name D2;129-Myod1<tm1Jae>
Former Common name MyoD-KO, D2-Myod1 KO
H-2 Haplotype No Data
Background strain No Data
Appearance
1 Appearance No Data
Genotype No Data
Strain development Developed by Rudolf Jaenisch, Whitehead Institute and Department of Biology Massachusetts Institute of Technology Cambridge. J1 ES cells were used. The mutant mice were maintained by Naohiro Hashimoto, National Center for Geriatrics and Gerontology. 129 and DBA/2 mixed background.
Strain description MyoD1 gene knockout mice. The Myod1 promoter, exon 1 and half of intron 1 were replaced with a a neomycin cassette.
Colony maintenance Homozygote x Homozygote
Health Report
Gene Details
Promoter No Data
1 Symbol Myod1
Symbol name myogenic differentiation 1
Chromosome 7
Common name No Data
Symbol description No Data
Promoter mouse phosphoglycerate kinase promoter (PGK promoter)
2 Symbol neo
Symbol name neomycin resistance gene (Klebsiella pneumoniae)
Chromosome 7
Common name No Data
Symbol description No Data
References

Research applications Mouse Models for Human Disease
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested.
Cell, 71, 383-390 (1992).
Additional information
1 No Data
2 Genotyping protocol <PCR>
Depositor Hashimoto, Naohiro (National Institute for Longevity Sciences) Hashimoto, Naohiro
Strain Status /
Availability
(Expected delivery)


Frozen
Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months

Sperm
Cryopreserved sperm : Within 1 month
Recovered litters from cryopreserved sperm : 2-4 months