RBRC06446, B6.129-Clmp<tm1Jwada>

RBRC No. RBRC06446
Type Targeted MutationCartagena
Species Mus musculus
Strain name B6.129-Clmp<tm1Jwada>
Former Common name B6-ACAM KO B6-Clmp KO
H-2 Haplotype No Data
ES cell line Not specified (ES cell)
Background strain No Data
Appearance
1 Appearance No Data
Genotype No Data
Strain development Developed by Jun Wada, Okayama University Graduate School of Medicine, Yoichiro Iwakura, The Institute of Medical Science, The University of Tokyo (Research Institute for Biomedical Sciences, Tokyo University of Science) in 2008. 129P2/OlaHsd derived ES cells were used to generate the mutant mice.
Strain description ACAM (CLMP) gene knockout mice. Exons 3 and 4 of the ACAM gene was replaced with a floxed-neo cassette. Homozygous mutant mice of C57BL/6 background show a severe growth defect and die by about 6 weeks of age. Homozygous mutant mice of ICR background show and increased birth rate, but die by 14 weeks of age. C57BL/6 background (RBRC06446), ICR background (RBRC06447), B6/ICR mixed (RBRC06448).
Colony maintenance Heterozygote x Wild-type [C57BL/6JJcl]
Health Report No Data
Gene Details
Promoter No Data
1 Symbol Clmp
Symbol name CXADR-like membrane protein
Chromosome 9
Common name No Data
Symbol description No Data
2 Symbol GH
Symbol name Growth hormone polyA (Bovine)
Chromosome 9
Common name No Data
Symbol description No Data
3 Symbol loxP
Symbol name phage P1 loxP
Chromosome 9
Common name No Data
Symbol description No Data
Promoter mouse phosphoglycerate kinase promoter (PGK promoter)
4 Symbol neo
Symbol name neomycin resistance gene (E. coli)
Chromosome 9
Common name No Data
Symbol description No Data
References

Research applications Cre/loxP system
Specific Term and Conditions No specific terms and conditions. (The DEPOSITOR waives its own rights under any patents, intellectual property, or other proprietary rights with respect to the results to be obtained by use of the BIOLOGICAL RESOURCE.)
Additional information
1 No Data
Depositor Wada, Jun (Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences) Wada, Jun
Strain Status /
Availability
(Expected delivery)


Sperm
Cryopreserved sperm : Within 1 month
Recovered litters from cryopreserved sperm : 2-4 months