Strain Information | |
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Image | |
BRC No. | RBRC06557 |
Type | Chemically-induced Mutation |
Species | Mus musculus |
Strain name | B6(D2)-Sufu<Rgsc2075> |
Former Common name | SufuR146X, B6-Sufu/R146X |
H-2 Haplotype | |
ES Cell line | |
Background strain | C57BL/6JJcl |
Appearance | |
Strain development | Developed by Shigeru Makino and Yoichi Gondo, RIKEN BioResource center. Generated by RIKEN ENU-based gene driven mutagenesis. The mutant mice were backcrossed to C57BL/6J. |
Strain description | Sufu gene ENU mutant mice. Sufu<Rgsc2062>(T396I variant)(RBRC06556): Homozygous mutant mice are embryonic lethal. Sufu<Rgsc2075>(R396X variant)(RBRC06557): Homozygous mutant mice die around E10. |
Colony maintenance | Heterozygote x Wild-type [C57BL/6JJcl] |
References | Nat Rev Genet., 9, 803-810 (2008). 18781157 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Sufusuppressor of fused homolog (Drosophila)19Sufu<Rgsc2075>RIKEN Genomic Sciences Center (GSC), 2075 |
Ordering Information | |
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Donor DNA | |
Research application | Cancer Research Developmental Biology Research Neurobiology Research |
Specific Term and Conditions | In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. (will be announced.) |
Depositor | Yoichi Gondo (RIKEN GSC) |
Strain Status | Frozen sperm |
Strain Availability | Recovered litters from cryopreserved sperm (2 to 4 months) Cryopreserved sperm (within 1 month) |
Additional Info. | Necessary documents for ordering: |
BRC mice in Publications |
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No Data |