Strain Data Sheet

RBRC06557

Strain Information

Image
BRC No.RBRC06557
TypeChemically-induced Mutation
SpeciesMus musculus
Strain nameB6(D2)-Sufu<Rgsc2075>
Former Common nameSufuR146X, B6-Sufu/R146X
H-2 Haplotype
ES Cell line
Background strainC57BL/6JJcl
Appearance
Strain developmentDeveloped by Shigeru Makino and Yoichi Gondo, RIKEN BioResource center. Generated by RIKEN ENU-based gene driven mutagenesis. The mutant mice were backcrossed to C57BL/6J.
Strain descriptionSufu gene ENU mutant mice. Sufu<Rgsc2062>(T396I variant)(RBRC06556): Homozygous mutant mice are embryonic lethal. Sufu<Rgsc2075>(R396X variant)(RBRC06557): Homozygous mutant mice die around E10.
Colony maintenanceHeterozygote x Wild-type [C57BL/6JJcl]
ReferencesNat Rev Genet., 9, 803-810 (2008). 18781157

Health Report

Examination Date / Room / Rack

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Sufusuppressor of fused homolog (Drosophila)19Sufu<Rgsc2075>RIKEN Genomic Sciences Center (GSC), 2075

Ordering Information

Donor DNA
Research applicationCancer Research
Developmental Biology Research
Neurobiology Research
Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. (will be announced.)
DepositorYoichi Gondo (RIKEN GSC)
Strain Statusan icon for Frozen spermFrozen sperm
Strain AvailabilityRecovered litters from cryopreserved sperm (2 to 4 months)
Cryopreserved sperm (within 1 month)
Additional Info.Necessary documents for ordering:
  1. Order form (Japanese / English)
  2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)

BRC mice in Publications

No Data