RBRC09238, C57BL/6-Tg(CAG-CCND1)14Hzi

RBRC No. RBRC09238
Type TransgeneCartagena
Species Mus musculus
Strain name C57BL/6-Tg(CAG-CCND1)14Hzi
Former Common name D1b14F, B6-CAG-CCND1 Tg#14
H-2 Haplotype No Data
Background strain C57BL/6JJcl
Appearance
1 Appearance No Data
Genotype No Data
Strain development Developed by Hirokazu Inoue, Shiga University of Medical Science and Gen Kondoh, Institute for Frontier Medical Science. The transgene was injected into the pronuclei of C57BL/6 fertilized eggs.
Strain description Cyclin D1b transgenic mice in which the human cyclin D1b transgene was driven by a pCAGGS promoter. Tg females develop rectal tumoers within 4 to 12 months after birth (female: 60%, male: 4%). The transgene was inserted into the intron region in chromosome 7 (7qA1).
Colony maintenance Carrier x Noncarrier [C57BL/6JJcl]
Health Report No Data
Gene Details
Promoter No Data
1 Symbol FLAG
Symbol name FLAG tag (synthetic)
Chromosome 7
Common name No Data
Symbol description No Data
Promoter CAG promoter (CMV-IE enhancer, chicken beta-actin promoter, rabbit beta-globin genomic DNA)
2 Symbol CCND1
Symbol name cyclin D1 (human)
Chromosome 7
Common name No Data
Symbol description No Data
References

Research applications Cancer Research,
Cell Biology Research,
Mouse Models for Human Disease
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
Prior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form.
Additional information
1 No Data
Depositor Inoue, Hirokazu (Shiga University of Medical Science) Inoue, Hirokazu
Strain Status /
Availability
(Expected delivery)


Sperm
Cryopreserved sperm : Within 1 month
Recovered litters from cryopreserved sperm : 2-4 months