RBRC09248, CHe.129-Trp53<tm1Brd>

RBRC No. RBRC09248
Type Targeted MutationCartagena
Species Mus musculus
Strain name CHe.129-Trp53<tm1Brd>
Former Common name BALB/c-Trp53 KO, BALB-p53 KO
H-2 Haplotype No Data
ES cell line AB1 [129S7/SvEvBrd-Hprt<+>]
Background strain BALB/cHeA
Appearance
1 Appearance No Data
Genotype No Data
Strain development Peter Demant, The Netherlands Cancer Institute to Osaka Prefecture University. The mutant mice were backcrossed to BALB/cHeA over 10 times.
Strain description Trp53 knockout mice, BALB/cHeA background. Homozygous mutant mice can grow after birth, but die within a few months after birth due to the development of tumors.
Colony maintenance Heterozygote x Wild-type [or Crossing to BALB/cHeAHiOpu (RBRC09247)]
Health Report
Gene Details
Promoter No Data
1 Symbol Trp53
Symbol name transformation related protein 53
Chromosome 11
Common name No Data
Symbol description No Data
Promoter mouse polymerase II promoter
2 Symbol neo
Symbol name neomycin resistance gene (E. coli)
Chromosome 11
Common name No Data
Symbol description No Data
References

Research applications Cancer Research
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
The availability of the BIOLOGICAL RESOURCE is limited to a RECIPIENT of a not-for profit institution for a not-for-profit research.
Additional information
1 No Data
2 Genotyping protocol <PCR>
Depositor Mori, Nobuko (Osaka Prefecture University) Mori, Nobuko
Strain Status /
Availability
(Expected delivery)


Frozen
Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months

Sperm
Cryopreserved sperm : Within 1 month
Recovered litters from cryopreserved sperm : 2-4 months