| RBRC No. | RBRC09691 |
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|---|---|---|---|---|---|---|---|
| Type | Transgene |
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| Species | Mus musculus | ||||||
| Strain name | C.C3-Tg(CAG-Il1rl1,CAG-GFP)23Tomi | ||||||
| Former Common name | No Data | ||||||
| H-2 Haplotype | No Data | ||||||
| Background strain | No Data | ||||||
| Appearance | |||||||
| 1 | Appearance | No Data | |||||
| Genotype | No Data | ||||||
| Strain development | Developed by Shin-ichi Tominaga and Kenji Kuroiwa, Jichi Medical University. DNA constructs (CAG-Il1rl1 and CAG-GFP) were injected to fertilized eggs derived from C3H/HeJ. Mice were backcrossed to BALB/c for 7 generations. | ||||||
| Strain description | Transgenic mice expressing GFP and a secreted form of Il1rl1 (interleukin 1 receptor-like 1; alternative name, ST2) under the control of CAG promoter. Hundreds ng/ml of ST2 can be detected in serum of transgenic mice. Related transgenic mouse lines are available as RBRC09692 and RBRC09693. | ||||||
| Health Report | No Data | ||||||
| Gene Details | |||||||
| Promoter | CAG promoter (CMV-IE enhancer, chicken beta-actin promoter, rabbit beta-globin genomic DNA) | ||||||
| 1 | Symbol | GFP (S65T/S147P) | |||||
| Symbol name | Green Fluorescent Protein (Jellyfish) | ||||||
| Chromosome | UN | ||||||
| Common name | No Data | ||||||
| Symbol description | No Data | ||||||
| 2 | Symbol | Il1rl1 | |||||
| Symbol name | interleukin 1 receptor-like 1 | ||||||
| Chromosome | UN | ||||||
| Common name | No Data | ||||||
| Symbol description | No Data | ||||||
| References | No Data | ||||||
| Research applications | Fluorescent Proteins/lacZ System | ||||||
| Specific Term and Conditions | The following terms and conditions will be requested by the DEPOSITOR. Prior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the Dr. Tsukasa Ohmori, Jichi Medical University using the Approval Form. The RECIPIENT agrees to use this BIOLOGICAL RESOURCE as a collaboration with the DEPOSITOR. |
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| Additional information | |||||||
| 1 | GFP Transfer License (Japanese / English) Please fill in the Schedule A, and submit two signed copies to us together with two signed copies of RIKEN BRC’s MTA. Please also read Schedule B. |
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| 2 | Genotyping protocol <PCR> | ||||||
| Depositor | Tominaga, Shin-ichi (Jichi Medical University)  |
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| Strain Status / Availability (Expected delivery) |
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